NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Untargeted metabolomics analysis of esophageal squamous cell cancer progression

T Yang, R Hui, J Nouws, M Sauler, T Zeng… - Journal of translational …, 2022 - Springer
Abstract 90% of esophageal cancer are esophageal squamous cell carcinoma (ESCC) and
ESCC has a very poor prognosis and high mortality. Nevertheless, the key metabolic …

The biology and mathematical modelling of glioma invasion: a review

JCL Alfonso, K Talkenberger… - Journal of the …, 2017 - royalsocietypublishing.org
Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …

Recent advances in targeted and untargeted metabolomics by NMR and MS/NMR methods

K Bingol - High-throughput, 2018 - mdpi.com
Metabolomics has made significant progress in multiple fronts in the last 18 months. This
minireview aimed to give an overview of these advancements in the light of their contribution …

Metabolomics technology and bioinformatics for precision medicine

RK Azad, V Shulaev - Briefings in bioinformatics, 2019 - academic.oup.com
Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

[HTML][HTML] Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy

C Ding, Z Shan, M Li, H Chen, X Li, Z Jin - Molecular Therapy-Oncolytics, 2021 - cell.com
Colorectal cancer (CRC) is one of the most common malignant tumors, with the second-
highest mortality of all 36 cancers worldwide. The roles of fatty acid metabolism in CRC were …

Challenges and opportunities in cancer metabolomics

A Kumar, BB Misra - Proteomics, 2019 - Wiley Online Library
Challenges in metabolomics for a given spectrum of disease are more or less comparable,
ranging from the accurate measurement of metabolite abundance, compound annotation …

A comparison of different machine-learning techniques for the selection of a panel of metabolites allowing early detection of brain tumors

A Godlewski, M Czajkowski, P Mojsak, T Pienkowski… - Scientific Reports, 2023 - nature.com
Metabolomics combined with machine learning methods (MLMs), is a powerful tool for
searching novel diagnostic panels. This study was intended to use targeted plasma …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …