The first crystal structure of CD8αα from a cartilaginous fish
Introduction Cartilaginous fishes are the most evolutionary-distant vertebrates from
mammals and possess an immunoglobulin (Ig)-and T cell-mediated adaptive immunity. CD8 …
mammals and possess an immunoglobulin (Ig)-and T cell-mediated adaptive immunity. CD8 …
Structural insights into the evolution feature of a bony fish CD8αα homodimer
J Wang, N Zhang, Z Wang, W Yanan, L Zhang… - Molecular immunology, 2018 - Elsevier
The CD8αα homodimer structures of endotherms demonstrate that despite distinct diversity
at the amino acid sequence level, a few conserved key amino acids ensure common …
at the amino acid sequence level, a few conserved key amino acids ensure common …
The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species
Y Liu, X Li, J Qi, N Zhang, C Xia - Scientific Reports, 2016 - nature.com
It is unclear how the pivotal molecules of the adaptive immune system (AIS) maintain their
inherent characteristics and relationships with their co-receptors over the course of co …
inherent characteristics and relationships with their co-receptors over the course of co …