Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients

R Bellmann, P Smuszkiewicz - Infection, 2017 - Springer
Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Antifungals: mechanism of action and drug resistance

R Prasad, AH Shah, MK Rawal - Yeast Membrane Transport, 2016 - Springer
There are currently few antifungals in use which show efficacy against fungal diseases.
These antifungals mostly target specific components of fungal plasma membrane or its …

Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America

TF Patterson, GR Thompson III… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Invasive aspergillosis in solid‐organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

S Husain, JF Camargo - Clinical transplantation, 2019 - Wiley Online Library
These updated AST‐IDCOP guidelines provide information on epidemiology, diagnosis, and
management of Aspergillus after organ transplantation. Aspergillus is the most common …

[图书][B] 21st century guidebook to fungi

D Moore, GD Robson, APJ Trinci - 2020 - books.google.com
The mysterious world of fungi is once again unearthed in this expansive second edition. This
textbook provides readers with an all-embracing view of the kingdom fungi, ranging in scope …

Combinatorial strategies for combating invasive fungal infections

M Spitzer, N Robbins, GD Wright - Virulence, 2017 - Taylor & Francis
Invasive fungal infections are an important cause of human mortality and morbidity,
particularly for immunocompromised populations. However, there remains a paucity of …

Antifungals and drug resistance

CM Hossain, LK Ryan, M Gera, S Choudhuri, N Lyle… - Encyclopedia, 2022 - mdpi.com
Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …

[PDF][PDF] Epidemiology, diagnosis and treatment of fungal respiratory infections in the critically ill patient

J Garnacho-Montero, P Olaechea, F Alvarez-Lerma… - Rev Esp Quimioter, 2013 - seq.es
Epidemiología. Aunque los aislamientos de levaduras en secreciones respiratorias no son
infrecuentes en el paciente intubado, las evidencias hasta el año 2013 (y posteriores) no …

Susceptibility patterns of amphotericin B, itraconazole, posaconazole, voriconazole and caspofungin for isolates causing invasive mould infections from the SENTRY …

MA Pfaller, CG Carvalhaes, M Castanheira - Mycoses, 2023 - Wiley Online Library
We evaluated the activity of amphotericin B, itraconazole, posaconazole, voriconazole and
caspofungin against 1468 invasive moulds collected worldwide from 2018 to 2021. Most (> …

Approach to invasive pulmonary aspergillosis in critically ill patients

D Koulenti, J Garnacho-Montero… - Current opinion in …, 2014 - journals.lww.com
A high level of suspicion in critically ill patients presenting with Aspergillus-positive
respiratory tract cultures or nonresolving pulmonary infection may lead to earlier IPA …