Potent molecular-targeted therapies for gastro-entero-pancreatic neuroendocrine carcinoma

A Ooki, H Osumi, K Fukuda, K Yamaguchi - Cancer and Metastasis …, 2023 - Springer
Neuroendocrine neoplasms (NENs), which are characterized by neuroendocrine
differentiation, can arise in various organs. NENs have been divided into well-differentiated …

[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

European Neuroendocrine Tumour Society (ENETS) 2023 guidance paper for nonfunctioning pancreatic neuroendocrine tumours

B Kos‐Kudła, JP Castaño, T Denecke… - Journal of …, 2023 - Wiley Online Library
This ENETS guidance paper for well‐differentiated nonfunctioning pancreatic
neuroendocrine tumours (NF‐Pan‐NET) has been developed by a multidisciplinary working …

Expert Consensus Practice Recommendations of the North American Neuroendocrine Tumor Society for the management of high grade gastroenteropancreatic and …

JR Eads, TR Halfdanarson, T Asmis… - Endocrine-related …, 2023 - erc.bioscientifica.com
High-grade neuroendocrine neoplasms are a rare disease entity and account for
approximately 10% of all neuroendocrine neoplasms. Because of their rarity, there is an …

Phase II study of everolimus and temozolomide as first-line treatment in metastatic high-grade gastroenteropancreatic neuroendocrine neoplasms

S Morken, SW Langer, A Sundlöv… - British journal of …, 2023 - nature.com
Background The optimal treatment for metastatic high-grade gastroenteropancreatic (GEP)
neuroendocrine neoplasms when Ki-67≤ 55% is unknown. A prospective multi-centre …

Approach to the patient: insulinoma

J Hofland, JC Refardt, RA Feelders… - The Journal of …, 2024 - academic.oup.com
Insulinomas are hormone-producing pancreatic neuroendocrine neoplasms with an
estimated incidence of 1 to 4 cases per million per year. Extrapancreatic insulinomas are …

[177Lu] Lu-DOTA-TATE plus long-acting octreotide versus high‑dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well …

S Singh, D Halperin, S Myrehaug, K Herrmann… - The Lancet, 2024 - thelancet.com
Background There are currently no standard first-line treatment options for patients with
higher grade 2–3, well-differentiated, advanced, gastroenteropancreatic neuroendocrine …

A systematic review of therapeutic strategies in gastroenteropancreatic grade 3 neuroendocrine tumors

MD Donadio, ÂB Brito… - … Advances in Medical …, 2023 - journals.sagepub.com
Background: Gastroenteropancreatic (GEP) neuroendocrine neoplasms with Ki-67> 20%
were subdivided in the most recent 2019 World Health Organization histopathological …

SEOM-GETNE clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs)(2022)

JC Castillón, TA Gordoa, AC Bayonas… - Clinical and …, 2023 - Springer
Neuroendocrine neoplasms (NENs) are a heterogeneous family of tumors of challenging
diagnosis and clinical management. Their incidence and prevalence continue to rise mainly …

Responses to Medical Treatment in 192 patients with pancreatic neuroendocrine neoplasms referred to the Copenhagen Neuroendocrine Tumour Centre in 2000 …

SS Petersen, S Møller, C Slott, J Krogh, CP Hansen… - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors are a rare and heterogenous group of
neoplasms. Surgical resection is the only curative option. However, there has been an …