A comprehensive review of lysine-specific demethylase 1 and its roles in cancer
A Hosseini, S Minucci - Epigenomics, 2017 - Taylor & Francis
Histone methylation plays a key role in the regulation of chromatin structure, and its
dynamics regulates important cellular processes. The investigation of the role of alterations …
dynamics regulates important cellular processes. The investigation of the role of alterations …
NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas
L Meder, K König, L Ozretić… - … journal of cancer, 2016 - Wiley Online Library
Small cell lung cancers (SCLCs) and extrapulmonary small cell cancers (SCCs) are very
aggressive tumors arising de novo as primary small cell cancer with characteristic genetic …
aggressive tumors arising de novo as primary small cell cancer with characteristic genetic …
The role of Cdk5 in neuroendocrine thyroid cancer
Medullary thyroid carcinoma (MTC) is a neuroendocrine cancer that originates from
calcitonin-secreting parafollicular cells, or C cells. We found that Cdk5 and its cofactors p35 …
calcitonin-secreting parafollicular cells, or C cells. We found that Cdk5 and its cofactors p35 …
CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression
Epithelial-mesenchymal transition is a change of cellular plasticity critical for embryonic
development and tumor metastasis. CDK5 is a proline-directed serine/threonine kinase …
development and tumor metastasis. CDK5 is a proline-directed serine/threonine kinase …
[HTML][HTML] An insight into the emerging role of cyclin-dependent kinase inhibitors as potential therapeutic agents for the treatment of advanced cancers
Cancer denotes a pathological manifestation that is characterized by hyperproliferation of
cells. It has anticipated that a better understanding of disease pathogenesis and the role of …
cells. It has anticipated that a better understanding of disease pathogenesis and the role of …
A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m6A -dependent activation of multiple oncogenes
Y Luo, M He, J Yang, F Zhang, J Chen, X Wen… - Science China Life …, 2023 - Springer
Retinoblastoma, the most prevalent primary intraocular tumor in children, leads to vision
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
Small cell lung cancer, an epithelial to mesenchymal transition (EMT)-like cancer: significance of inactive Notch signaling and expression of achaete-scute complex …
T Ito, S Kudoh, T Ichimura, K Fujino, WAMA Hassan… - Human cell, 2017 - Springer
Small cell lung cancer (SCLC) is one of the most malignant neoplasms in common human
cancers. The tumor is composed of small immature-looking cells with a round or fusiform …
cancers. The tumor is composed of small immature-looking cells with a round or fusiform …
[HTML][HTML] Cellular and molecular biology of small cell lung cancer: an overview
Although the incidence of small cell lung cancer (SCLC) has declined during the past 30
years, it remains a frustrating disease to research and treat. Numerous attempts to enhance …
years, it remains a frustrating disease to research and treat. Numerous attempts to enhance …
Calcium channel TRPV6 promotes breast cancer metastasis by NFATC2IP
X Xu, N Li, Y Wang, J Yu, J Mi - Cancer Letters, 2021 - Elsevier
Calcium channel TRPV6 upregulation is associated with poor prognosis of breast cancer by
promoting invasion and metastasis, and TRPV6 is a potential target for breast cancer …
promoting invasion and metastasis, and TRPV6 is a potential target for breast cancer …