There is currently accumulating evidence that endogenous estrogens play a critical role in
the development of breast cancer. Estrogens and their metabolites have been studied in …

To assess the joint relationships among body mass index, menopausal status, and breast
cancer according to breast cancer subtype and estrogen-progestin medication use, we …

Purpose: MicroRNAs (miRNA) have potential prognostic value for colorectal cancers;
however, their value based on patient race/ethnicity and pathologic stage has not been …

Background Racial disparities in breast cancer survival have been well documented. This
study examines the association of race/ethnicity and socioeconomic status (SES) on breast …

Abstract UDP-glucuronyltransferase 1A1 (UGT1A1) is a member of the Phase II metabolic
enzyme family and the only enzyme that can metabolize detoxified bilirubin. Inactivation and …

Randomized, clinical trials have established the efficacy of screening mammography in
improving survival from breast cancer for women through detection of early, asymptomatic …

Abstract Catechol-O-methyltransferase, COMT, is an important phase II enzyme catalyzing
the transfer of a methyl-group from S-adenosylmethionine to a catechol-containing substrate …

Glutathione S-transferases (GSTs) are a family of phase II metabolizing enzymes involved in
carcinogen detoxification and the metabolism of various bioactive compounds. Several …

PURPOSE: This study aimed to evaluate the frequency of homozygous deletion of GSTM1
and GSTT1 genes and their combinations between patients with breast cancer and healthy …

Cytosolic sulfotransferases (SULTs) are phase II detoxification enzymes that are involved in
the biotransformation of a wide variety of structurally diverse endo-and xenobiotics. Single …