Membrane association is a hallmark of the genome replication of positive-strand RNA
viruses [(+) RNA viruses]. All well-studied (+) RNA viruses remodel host membranes and …

Highlights•+ RNA viruses build membranous VRCs.•+ RNA viruses rewire cellular lipid
metabolism to build VRCs.•VRC structure and formation mechanisms differ between …

Cardioviruses, including encephalomyocarditis virus (EMCV) and the human Saffold virus,
are small non-enveloped viruses belonging to the Picornaviridae, a large family of positive …

Lipids and lipoproteins constitute indispensable components for living not only for humans.
In the case of hepatitis C virus (HCV), the option of using the products of our lipid …

Highlights•(+) RNA virus replication compartments form two structural classes.•Both classes
of replication compartments use cellular membrane curvature proteins.•Both classes of …

Hepatitis C virus (HCV) is a major human pathogen that requires a better understanding of
its interaction with host cells. There is a close association of HCV life cycle with host lipid …

Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV
infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and …

Nanomedicine enables unique diagnostic and therapeutic capabilities to tackle problems in
clinical medicine. As multifunctional agents with programmable properties, nanomedicines …

The COVID-19 pandemic has reignited efforts to develop materials science innovations
aimed at stopping viral infections. One of the greatest opportunities lies in developing broad …

Type III phosphatidylinositol 4-kinase (PI4KIIIβ) is an essential enzyme in mediating
membrane trafficking and is implicated in a variety of pathogenic processes. It is a key host …