The retinal ganglion cells (RGCs) are the output cells of the retina into the brain. In
mammals, these cells are not able to regenerate their axons after optic nerve injury, leaving …

The death of retinal ganglion cells (RGCs) is a key factor in the pathophysiology of all types
of glaucoma, but the mechanism of pathogenesis of glaucoma remains unclear. RGCs are a …

Gene therapies, despite of being a relatively new therapeutic approach, have a potential to
become an important alternative to current treatment strategies in glaucoma. Since …

Magnesium acetyltaurate (MgAT) has been shown to have a protective effect against N-
methyl-D-aspartate (NMDA)-induced retinal cell apoptosis. The current study investigated …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive decline. Synaptic impairment is one of the first events to occur in …

Abstract Background Vitamin A (VitA), via its active metabolite retinoic acid (RA), is critical for
the maintenance of memory function with advancing age. Although its role in Alzheimer's …

Abstract N-Methyl-D-aspartate (NMDA)-induced neuronal cell death is involved in a large
spectrum of diseases affecting the brain and the retina such as Alzheimer's disease and …

Background In the field of autoimmune demyelinating diseases, visual impairments have
extensively been studied using the experimental autoimmune encephalomyelitis (EAE) …

The ability of the central nervous system to regenerate over long distances after a lesion is
restricted by the presence of physical and biochemical barriers, neuronal growth programs …

Glaucoma is considered a neurodegenerative disease characterized by progressive visual
field defects that may lead to blindness. Although controlling intraocular pressure (IOP) is the …