Glioma is a deadly form of brain cancer, and the difficulty of treating glioma is exacerbated
by the chemotherapeutic resistance developed in the tumor cells over the time of treatment …

Glioblastoma is the most malignant central nervous system tumor, which represents 50% of
all glial tumors. The understanding of glioma genesis, prognostic evaluation, and treatment …

A single-institution observational study with 43 newly diagnosed diffuse gliomas defined the
isocitrate dehydrogenase 1 and 2 (IDH1/2) gene mutation status and evaluated the …

Actin-related protein 2/3 complex subunit 1A (ARPC1A) is implicated in several cancers due
to its critical role in regulating actin polymerization. However, the exact mechanism of …

Introduction Sex-related differences in the epidemiology of malignant gliomas are
acknowledged; however, information regarding their clinical characteristics and outcomes …

Comparative analysis of the conventional methylation-specific PCR (MSP) vs. the
quantitative MSP (qMSP) assessment of the O6-methylguanine-DNA methyltransferase …

Advances in nanotechnology have offered new possibilities in cancer detection and
treatment. Through the use of multifunctional nanoparticles, researchers aim to address …

Tóm tắt Đột biến gen IDH1 (IDH1-m) và sự methyl hóa gen MGMT (Methyl-MGMT) là những
dấu ấn sinh học phân tử đóng vai trò quan trọng trong tiên lượng đối với bệnh nhân mắc u …

The objective of this study was to analyse the prognosis values of O6-methylguanine-DNA
methyltransferase (MGMT) promoter methylation on the overall survival in patients with …

Savremeni terapijski pristupi u lečenju pacijenata obolelih od glioblastoma (GBM) oslanjaju
se na primenu alkilirajućih agenasa poput Temozolomida (“Stupp”-ov protokol) …