Placental mitochondrial function and dysfunction in preeclampsia

F Jahan, G Vasam, AE Green, SA Bainbridge… - International journal of …, 2023 - mdpi.com
The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …

Roles of mitochondrial DNA damage in kidney diseases: a new biomarker

J Feng, Z Chen, W Liang, Z Wei, G Ding - International Journal of …, 2022 - mdpi.com
The kidney is a mitochondria-rich organ, and kidney diseases are recognized as
mitochondria-related pathologies. Intact mitochondrial DNA (mtDNA) maintains normal …

Exposure to unmethylated CpG oligonucleotides disrupts blood pressure circadian rhythms and placental clock gene network in pregnant rats

JL Bradshaw, SC Cushen, CA Ricci… - American Journal …, 2023 - journals.physiology.org
Bacterial infections and impaired circulating mitochondrial DNA dynamics are associated
with adverse pregnancy outcomes. Unmethylated cytosine-guanine dinucleotide (CpG) …

[HTML][HTML] Pregnancy Disorders: A Potential Role for Mitochondrial Altered Homeostasis

JM Toledano, M Puche-Juarez, JM Galvez-Navas… - Antioxidants, 2024 - mdpi.com
Pregnancy is a complex and challenging process associated with physiological changes
whose objective is to adapt the maternal organism to the increasing energetic requirements …

Air pollution-linked epigenetic modifications in placental DNA: Prognostic potential for identifying future foetal anomalies

SH Kumar, S Acharyya, A Chouksey, N Soni… - Reproductive …, 2024 - Elsevier
Prenatal exposure to air pollution is a significant risk factor for the mother and the
developing foetus. The accumulation of pollutants in the placenta can cause a self-cascade …

Cardiac mitochondrial metabolism during pregnancy and the postpartum period

EB Schulman-Geltzer, KL Fulghum… - American Journal …, 2024 - journals.physiology.org
The goal of the present study was to characterize changes in mitochondrial respiration in the
maternal heart during pregnancy and after birth. Timed pregnancy studies were performed …

A Review on Inflammasomes and Immune Checkpoints in Pre-Eclampsia Complicated with Tuberculosis and Human Immune Deficiency Virus

WN Phoswa, OP Khaliq, S Eche - International Journal of Environmental …, 2023 - mdpi.com
The current review evaluates how inflammasomes and immune checkpoints are regulated in
pre-eclampsia (PE) associated with tuberculosis (TB) and Human Immune Deficiency Virus …

Mitochondrial might: powering the peripartum for risk and resilience

E Gorman-Sandler, G Wood, N Cloude… - Frontiers in Behavioral …, 2023 - frontiersin.org
The peripartum period, characterized by dynamic hormonal shifts and physiological
adaptations, has been recognized as a potentially vulnerable period for the development of …

Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells

JJ Gardner, SC Cushen… - … of Physiology-Cell …, 2024 - journals.physiology.org
Circulating cell-free mitochondrial DNA (ccf-mtDNA) is an indicator of cell death,
inflammation, and oxidative stress. ccf-mtDNA in pregnancies with placental dysfunction …

Role of mitochondrial DNA level in epidural-related maternal fever: a single-centre, observational, pilot study

C Hafner, M Windpassinger, EV Tretter… - BMC Pregnancy and …, 2024 - Springer
Introduction Epidural analgesia has been associated with intrapartum maternal fever
development. Epidural-related maternal fever (ERMF) is believed to be based on a non …