The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

A Yeast under Cover: the Capsule of Cryptococcus neoformans

I Bose, AJ Reese, JJ Ory, G Janbon, TL Doering - Eukaryotic cell, 2003 - Am Soc Microbiol
Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS …

Proteomic Analysis of Candida albicans Cell Walls Reveals Covalently Bound Carbohydrate-Active Enzymes and Adhesins

PWJ de Groot, AD de Boer, J Cunningham… - Eukaryotic …, 2004 - Am Soc Microbiol
Covalently linked cell wall proteins (CWPs) of the dimorphic fungus Candida albicans are
implicated in virulence. We have carried out a comprehensive proteomic analysis of the …

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

TR O'Meara, D Norton, MS Price, C Hay… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues in order to establish a human infection. We have identified the C …

Cryptococcus

SS Li, CH Mody - Proceedings of the American Thoracic Society, 2010 - atsjournals.org
Cryptococcus is a unique environmental fungus. Among the more than three dozen species
of Cryptococcus, only C. neoformans and C. gattii commonly cause disease. Although many …

Harnessing the immune response to fungal pathogens for vaccine development

A Rivera, J Lodge, C Xue - Annual review of microbiology, 2022 - annualreviews.org
Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

Chitin: a “hidden figure” in the fungal cell wall

HE Brown, SK Esher, JA Alspaugh - The fungal cell wall: an armour and a …, 2020 - Springer
Chitin and chitosan are two related polysaccharides that provide important structural stability
to fungal cell walls. Often embedded deeply within the cell wall structure, these molecules …

Virulence in Cryptococcus species

H Ma, RC May - Advances in applied microbiology, 2009 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals …