Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …

Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

A novel series of quinazolinone-1, 2, 3-triazole hybrids 10a-p were designed, synthesized,
and evaluated for their in vitro α-glucosidase inhibitory activity leading to efficient anti …

The synthesis of some 2-furano-4 (3H)-quinazolinones, diamides (open ring quinazolines),
quinoxalines and their biological evaluation as antitumor agents using National Cancer …

The heterocyclic compounds have a great importance in medicinal chemistry. One of the
most important heterocycles in medicinal chemistry are quinazolines possessing wide …

Presently cancer is a grave health issue with predominance beyond restrictions. It can affect
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …

Owing to the significant biological activities, quinazoline derivatives have drawn more and
more attention in the synthesis and bioactivities research. This review summarizes the …

Novel derivatives of quinazoline (1–27) have been synthesized and tested for their antitumor
activity against three tumor cell lines among these cell lines the human breast carcinoma …

Microtubules are cylindrical protein polymers formed from α β-tubulin heterodimers in the
cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the …

The synthesis of some new 3-substituted quinazolin-4 (3H)-ones and 3, 4-dihydro-
quinazolin-2 (1H)-one derivatives and their biological evaluation as antitumor agents using …