Pooling for SARS-CoV2 surveillance: Validation and strategy for implementation in K-12 schools

AM Simas, JW Crott, C Sedore, A Rohrbach… - Frontiers in public …, 2021 - frontiersin.org
Repeated testing of a population is critical for limiting the spread of the SARS-CoV-2 virus
and for the safe reopening of educational institutions such as kindergarten—grade 12 (K-12) …

[HTML][HTML] Swab pooling enables rapid expansion of high-throughput capacity for SARS-CoV-2 community testing

J Fagg, R Beale, ME Futschik, E Turek… - Journal of Clinical …, 2023 - Elsevier
Background The challenges of rapid upscaling of testing capacity were a major lesson from
the COVID-19 pandemic response. The need for process adjustments in high-throughput …

Determining diagnostic sensitivity loss limits for sample pooling in duplex rtPCR surveillance testing: Theileria orientalis and Anaplasma marginale

C Burgess, SM Todd, L Hungerford… - Journal of Veterinary …, 2024 - journals.sagepub.com
To expand surveillance testing capacity through sample pooling, a thorough understanding
is needed of how sample dilution through pooling affects the sensitivity of candidate assays …

Thinking beyond pathogen surveillance: building resilient biotech ecosystems to combat the next pandemic

MA Crone, PS Freemont - Frontiers in Science, 2024 - frontiersin.org
The lead article by Struelens et al.(1) offers a comprehensive look at the evolution of
pathogen surveillance during the SARS-CoV-2 pandemic and maps out how further …

Simple Low-Cost Production of DNA MS2 Virus-Like Particles As Molecular Diagnostic Controls

MA Crone, PS Freemont - GEN biotechnology, 2022 - liebertpub.com
Suitable controls are integral for the validation and continued quality assurance of
diagnostic workflows. Plasmids, DNA, or in vitro transcribed RNA are often used to validate …