Mucosal and cutaneous human papillomavirus infections and cancer biology

T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …

HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle

JC Lam, NG Aboreden, SC Midla, S Wang, A Huang… - Nature Genetics, 2024 - nature.com
Few transcription factors have been examined for their direct roles in physically connecting
enhancers and promoters. Here acute degradation of Yin Yang 1 (YY1) in erythroid cells …

Targeting transcription factor YY1 for cancer treatment: current strategies and future directions

R Hosea, S Hillary, S Wu, V Kasim - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a global health problem with severe consequences. Certain
genes, known as transcription factors (TFs), are overactive in many tumors. Targeting these …

YY1 regulates cancer cell immune resistance by modulating PD-L1 expression

E Hays, B Bonavida - Drug Resistance Updates, 2019 - Elsevier
Recent advances in the treatment of various cancers have resulted in the adaptation of
several novel immunotherapeutic strategies. Notably, the recent intervention through …

Epigenetic regulation of human papillomavirus transcription in the productive virus life cycle

M Burley, S Roberts, JL Parish - Seminars in immunopathology, 2020 - Springer
Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …

[HTML][HTML] The biological implications of Yin Yang 1 in the hallmarks of cancer

ITS Meliala, R Hosea, V Kasim, S Wu - Theranostics, 2020 - ncbi.nlm.nih.gov
Tumorigenesis is a multistep process characterized by the acquisition of genetic and
epigenetic alterations. During the course of malignancy development, tumor cells acquire …

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

EL Morgan, JA Scarth, MR Patterson… - Cell Death & …, 2021 - nature.com
Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing
to~ 5% of all human cancers including almost all cases of cervical cancer and a growing …

Epigenetic regulation of the human papillomavirus life cycle

M Mac, CA Moody - Pathogens, 2020 - mdpi.com
Persistent infection with certain types of human papillomaviruses (HPVs), termed high risk,
presents a public health burden due to their association with multiple human cancers …

Control of viral latency by episome maintenance proteins

A De Leo, A Calderon, PM Lieberman - Trends in microbiology, 2020 - cell.com
The human DNA tumor viruses Epstein–Barr virus (EBV), Kaposi's sarcoma-associated
herpesvirus (KSHV), and human papillomavirus (HPV) share the common property of …