Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis

S Zhang, Y Liu, Y Cao, S Zhang, J Sun… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis

J Chen, X Zhang, R Millican, J Sherwood… - Advanced drug delivery …, 2021 - Elsevier
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries,
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …

Targeting Theranostics of Atherosclerosis by Dual‐Responsive Nanoplatform via Photoacoustic Imaging and Three‐In‐One Integrated Lipid Management

B Ma, Y Xiao, Q Lv, G Li, Y Wang, G Fu - Advanced Materials, 2023 - Wiley Online Library
Atherosclerosis, as a life‐threatening cardiovascular disease with chronic inflammation and
abnormal lipid enrichment, is often difficult to treat timely due to the lack of obvious …

Recent Progress in in vitro Models for Atherosclerosis Studies

J Chen, X Zhang, R Millican, T Lynd… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Nanodiscs: Game changer nano-therapeutics and structural biology tools

AO Elzoghby, O Samir, A Soliman, S Solomevich, M Yu… - Nano Today, 2023 - Elsevier
In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …

Disrupted lipid metabolism in multiple sclerosis: a role for liver X receptors?

I Pineda-Torra, S Siddique, KE Waddington… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is a chronic neurological disease driven by autoimmune,
inflammatory and neurodegenerative processes leading to neuronal demyelination and …

Immune Implications of Cholesterol-Containing Lipid Nanoparticles

PI Back, M Yu, S Modaresahmadi, S Hajimirzaei… - ACS …, 2024 - ACS Publications
The majority of clinically approved nanoparticle-mediated therapeutics are lipid
nanoparticles (LNPs), and most of these LNPs are liposomes containing cholesterol. LNP …

Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation

Y Luo, Y Guo, H Wang, M Yu, K Hong, D Li, R Li… - …, 2021 - thelancet.com
Background Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause
of mortality worldwide. Cholesterol crystals (CCs) induce inflammation in atherosclerosis …

Advances in imaging and treatment of atherosclerosis based on organic nanoparticles

S Tu, W He, J Han, A Wu, W Ren - APL bioengineering, 2022 - pubs.aip.org
Atherosclerosis, a systemic chronic inflammatory disease, can lead to thrombosis and
vascular occlusion, thereby inducing a series of serious vascular diseases. Currently …

Harnessing anti-inflammatory pathways and macrophage nano delivery to treat inflammatory and fibrotic disorders

A Zaid, A Ariel - Advanced Drug Delivery Reviews, 2024 - Elsevier
Targeting specific organs and cell types using nanotechnology and sophisticated delivery
methods has been at the forefront of applicative biomedical sciences lately. Macrophages …