Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …

Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Metal complexes with N-heterocyclic carbene (NHC) ligands are widely used in chemistry
due to their catalytic properties and applied for olefin metathesis among other reactions. The …

Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …

Silver is proving to have a number of medicinal applications; as an antiseptic, an
antibacterial, and an anti-inflammatory, while any biological role for it is currently unknown …

From their early successes in medicine, organometallic compounds continue to attract
interest as potential chemotherapeutics to treat a range of diseases. Here, we show from …

Cancer is a complex issue and, even though the prevention basics and therapy have been
implemented, it is still the second leading death cause worldwide. With the hope to discover …

Introduction Cancer has been identified as one of the leading causes of death worldwide.
The biological target of some anticancer agents is topoisomerase I, an enzyme involved in …

N‐Heterocyclic carbenes (NHCs) complexed with silver represent new, broad‐spectrum
antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a …