Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …

The ongoing biomedical nanotechnology has intrigued increasingly intense interests in
cerium oxide nanoparticles, ceria nanoparticles or nano-ceria (CeO2-NPs). Their …

Background: For decades, regenerative medicine and dentistry have been improved with
new therapies and innovative clinical protocols. The aim of the present investigation was to …

The bone morphogenetic proteins (BMPs) are a group of potent morphogens which are
critical for the patterning, development, and function of the central nervous system. The …

Transfer of regenerative approaches into clinical practice is limited by strict legal regulation
of in vitro expanded cells and risks associated with substantial manipulations. Isolation of …

Background: The process of the globally aging population has been accelerating, leading to
an increasing social burden. As people age, the musculoskeletal system will gradually go …

BACKGROUND Efficient bone regeneration using recombinant human bone morphogenetic
protein-2 (BMP-2) is needed to reduce side effects caused by high-dose BMP-2 use. The …

Biomaterials play an important role in treating bone defects. The functional characteristics of
scaffolds, such as their structure, mechanical strength, and antibacterial and osteogenesis …

Bone defects, which can be caused by factors such as trauma, tumor, or osteomyelitis, are
clinically common. They lessen the weight a bone is able to bear and cause severe pain to …

The discovery of bone morphogenetic proteins (BMPs) inspired hope for the successful
treatment of bone disorders, but side effects worsening the clinical effects were eventually …