Structural characterization of open reading frame-encoded functional genes from tilapia lake virus (TiLV)

V Acharya, HJ Chakraborty, AK Rout… - Molecular …, 2019 - Springer
In recent years, large-scale mortalities are observed in tilapia due to infection with a novel
orthomyxo-like virus named, tilapia lake virus (TiLV) which is marked to be a severe threat to …

Structural insights into the RNA interaction with Yam bean Mosaic virus (coat protein) from Pachyrhizus erosus using bioinformatics approach

V Acharya, R Arutselvan, K Pati, AK Rout, B Dehury… - Plos one, 2022 - journals.plos.org
Plants are constantly threatened by a virus infection, ie, Potyviruses, the second largest
genus of plant viruses which results in several million-dollar losses in various essential …

Gene expression profiling of sepsis-associated acute kidney injury

JJ Yang, BB Wu, F Han… - Experimental and …, 2020 - spandidos-publications.com
Sepsis accounts for more than 50% of all acute kidney injury (AKI) cases, and the
combination of sepsis and AKI increases the risk of mortality from sepsis alone. However, to …

Insights into structure and dynamics of extracellular domain of Toll-like receptor 5 in Cirrhinus mrigala (mrigala): A molecular dynamics simulation approach

AK Rout, V Acharya, D Maharana, B Dehury… - PloS one, 2021 - journals.plos.org
The toll-like receptor 5 (TLR5) is the most conserved important pattern recognition receptors
(PRRs) often stimulated by bacterial flagellins and plays a major role in the first-line defense …

Characterisation of LGP2 complex multitranscript system in humans: role in the innate immune response and evolution from non-human primates

J Martinez-Laso, I Cervera… - Human Molecular …, 2024 - academic.oup.com
Retinoic acid inducible gene I (RIG-I)-like receptors (RLRs), including RIG-I, MDA5 and
LGP2, recognize viral RNA to mount an antiviral interferon (IFN) response RLRs share three …

Interaction analysis of TRIM proteins and innate immunity mediators of common carp (Cyprinus carpio L.) to evaluate its affinity for ubiquitination and innate immune …

M Aizaz, M Nisar, RZ Paracha, S Shan, NF Ali, I Arshad… - Aquaculture, 2023 - Elsevier
Common carp (Cyprinus carpio L.) is considered the most important aquaculture piscine
specie. The continuous exposure of this specie to pathogens, including viruses and bacteria …

Alternative splicing generates a novel ferroportin isoform with a shorter C‐terminal and an intact iron‐and hepcidin‐binding property

P Juneja, N Rashid, F Abul Qais, S Tanwar… - IUBMB …, 2024 - Wiley Online Library
Ferroportin (FPN) is a transmembrane protein and is the only known iron exporter that helps
in maintaining iron homeostasis in vertebrates. To maintain stable iron equilibrium in the …

Elucidating the molecular interaction of Zebrafish (Danio rerio) peptidoglycan recognition protein 2 with diaminopimelic acid and lysine type peptidoglycans using in …

AK Rout, S Paramanik, B Dehury… - Journal of …, 2020 - Taylor & Francis
Peptidoglycan recognition proteins (PGRPs) belong to the family of pattern recognition
receptor, represent the major constituent of innate immunity. Although PGRPs are …

Molecular characterization, constitutive expression and GTP binding mechanism of Cirrhinus mrigala (Hamilton, 1822) Myxovirus resistance (Mx) protein

P Roy, AK Rout, J Maharana, DR Sahoo… - International journal of …, 2019 - Elsevier
Myxovirus resistance (Mx) proteins represents the subclass of the dynamin superfamily of
large Guanosine triphosphates (GTPases), play esential role in intracellular vesicle …

Toxoplasma gondii aspartic protease 5: structural basis of substrate binding and inhibition mechanism

S Chakraborty, A Deshmukh, P Kesari… - Journal of Biomolecular …, 2024 - Taylor & Francis
Toxoplasma gondii, a worldwide prevalent parasite is responsible for causing toxoplasmosis
in almost all warm-blooded animals, including humans. Golgi-resident T. gondii aspartic …