The ability to generate induced pluripotent stem cells (iPSCs) from patients, and an
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …

Listen to an interview with Tom Rando on the stem cells podcast Adult stem cells reside in
most mammalian tissues, but the extent to which they contribute to normal homeostasis and …

Because of their somatic cell origin, human induced pluripotent stem cells (HiPSCs) are
assumed to carry a normal diploid genome, and adaptive chromosomal aberrations have …

Abstract The International Stem Cell Initiative analyzed 125 human embryonic stem (ES) cell
lines and 11 induced pluripotent stem (iPS) cell lines, from 38 laboratories worldwide, for …

Abstract The International Stem Cell Initiative characterized 59 human embryonic stem cell
lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques …

The application of human embryonic stem cells (HESCs) to provide differentiated cells for
regenerative medicine will require the continuous maintenance of the undifferentiated stem …

Although distinct human induced pluripotent stem cell (hiPSC) lines can display
considerable epigenetic variation, it has been unclear whether such variability impacts their …

Human embryonic stem cells (HESCs) are the in vitro descendants of the pluripotent inner
cell mass (ICM) of human blastocyst stage embryos. HESCs can be kept undifferentiated in …

Tissue engineering is a newly emerging biomedical technology, which aids and increases
the repair and regeneration of deficient and injured tissues. It employs the principles from …

Studies using high-resolution genome-wide approaches have recently reported that
genomic and epigenomic alterations frequently accumulate in human pluripotent cells …