The interplay of organ-of-Corti vibrational modes, not tectorial-membrane resonance, sets outer-hair-cell stereocilia phase to produce cochlear amplification

JJ Guinan Jr - Hearing research, 2020 - Elsevier
The mechanical motions that deflect outer-hair-cell (OHC) stereocilia and the resulting
effects of OHC motility are reviewed, concentrating on high-frequency cochlear regions. It …

Cochlear amplification in the short-wave region by outer hair cells changing organ-of-Corti area to amplify the fluid traveling wave

JJ Guinan Jr - Hearing Research, 2022 - Elsevier
Many details of the operation of the mammalian cochlea are known, but how they all work
together to produce cochlear amplification is not understood. Outer-hair-cell (OHC) motility …

Characterizing a joint reflection-distortion OAE profile in humans with endolymphatic hydrops

S Stiepan, CA Shera, C Abdala - Ear and Hearing, 2023 - journals.lww.com
Objectives: Endolymphatic hydrops (EH), a hallmark of Meniere disease, is an inner-ear
disorder where the membranes bounding the scala media are distended outward due to an …

Intracochlear distortion products are broadly generated by outer hair cells but their contributions to otoacoustic emissions are spatially restricted

T Bowling, H Wen, SWF Meenderink, W Dong… - Scientific Reports, 2021 - nature.com
Detection of low-level sounds by the mammalian cochlea requires electromechanical
feedback from outer hair cells (OHCs). This feedback arises due to the electromotile …

Denoising click-evoked otoacoustic emission signals by optimal shrinkage

TC Liu, YW Liu, HT Wu - The Journal of the Acoustical Society of …, 2021 - pubs.aip.org
Click-evoked otoacoustic emissions (CEOAEs) are clinically used as an objective way to
infer whether cochlear functions are normal. However, because the sound pressure level of …

Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis

JJ Guinan Jr, SM Lefler, CA Buchman, SS Goodman… - Scientific reports, 2021 - nature.com
A fundamental property of mammalian hearing is the conversion of sound pressure into a
frequency-specific place of maximum vibration along the cochlear length, thereby creating a …

Outer hair cells can amplify the fluid traveling wave by changing organ-of-Corti area in the short-wave region

JJ Guinan - AIP Conference Proceedings, 2024 - pubs.aip.org
There are two kinds of cochlear amplification:“non-propagating amplification” that is
widespread but doesn't couple to the traveling wave, and “traveling-wave amplification” that …

Medial olivocochlear reflex effects on amplitude growth functions of long-and short-latency components of click-evoked otoacoustic emissions in humans

SS Goodman, S Boothalingam… - Journal of …, 2021 - journals.physiology.org
Functional outcomes of medial olivocochlear reflex (MOCR) activation, such as improved
hearing in background noise and protection from noise damage, involve moderate to high …

The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips

SS Goodman, SM Lefler, C Lee, JJ Guinan Jr… - Journal of the …, 2024 - Springer
Purpose Tone-pip-evoked otoacoustic emissions (PEOAEs) are transient-evoked
otoacoustic emissions (OAEs) that are hypothesized to originate from reflection of energy …

Human Olivocochlear Effects: A Statistical Detection Approach Applied to the Cochlear Microphonic Evoked by Swept Tones

SS Goodman, S Haysley, SG Jennings - … of the Association for Research in …, 2024 - Springer
The human medial olivocochlear (MOC) reflex was assessed by observing the effects of
contralateral acoustic stimulation (CAS) on the cochlear microphonic (CM) across a range of …