[HTML][HTML] Mechanisms of short-chain fatty acids derived from gut microbiota in Alzheimer's disease

X Qian, R Xie, X Liu, H Tang - Aging and disease, 2022 - ncbi.nlm.nih.gov
Short-chain fatty acids (SCFAs) are important metabolites derived from the gut microbiota
through fermentation of dietary fiber. SCFAs participate a number of physiological and …

Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease

L Bonfili, V Cecarini, O Gogoi, C Gong… - The FEBS …, 2021 - Wiley Online Library
The gut microbiota coevolves with its host, and numerous factors like diet, lifestyle, drug
intake and geographical location continuously modify its composition, deeply influencing …

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

TJ Wenzel, EJ Gates, AL Ranger, A Klegeris - Molecular and Cellular …, 2020 - Elsevier
Neuroinflammation contributes to neurodegenerative disorders, including Alzheimer's
disease (AD). Gut microbes are involved in regulating systemic inflammation. Short-chain …

Effect of Clostridium butyricum against Microglia‐Mediated Neuroinflammation in Alzheimer's Disease via Regulating Gut Microbiota and Metabolites Butyrate

J Sun, J Xu, B Yang, K Chen, Y Kong… - Molecular nutrition & …, 2020 - Wiley Online Library
Scope Recent evidences demonstrate that abnormal gut microbiota (GM) might be involved
in the pathogenesis of Alzheimer's disease (AD). However, the role of probiotics in …

Multiple roles of short-chain fatty acids in Alzheimer disease

H Chen, L Meng, L Shen - Nutrition, 2022 - Elsevier
Alzheimer disease (AD) is the most common form of neurodegenerative disease in older
adults and has a complicated etiology. Recently, the roles of short-chain fatty acids (SCFAs) …

Dietary fiber modulates the release of gut bacterial products preventing cognitive decline in an Alzheimer's mouse model

D Cuervo-Zanatta, T Syeda, V Sánchez-Valle… - Cellular and molecular …, 2023 - Springer
Fiber intake is associated with a lower risk for Alzheimer´ s disease (AD) in older adults.
Intake of plant-based diets rich in soluble fiber promotes the production of short-chain fatty …

[HTML][HTML] Gut-brain axis through the lens of gut microbiota and their relationships with Alzheimer's disease pathology: review and recommendations

L Krishaa, TKS Ng, HN Wee, J Ching - Mechanisms of Ageing and …, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people
worldwide. Growing evidence suggests that the gut microbiome (GM) plays a pivotal role in …

Alzheimer's disease and diabetes: Role of diet, microbiota and inflammation in preclinical models

MJ Carranza-Naval, M Vargas-Soria… - Biomolecules, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia. Epidemiological studies
show the association between AD and type 2 diabetes (T2DM), although the mechanisms …

The common marmoset as a model of neurodegeneration

C Perez-Cruz, J de Dios Rodriguez-Callejas - Trends in Neurosciences, 2023 - cell.com
Human life expectancy has increased over the past few centuries, and the incidence of
dementia in the older population is also projected to continue to rise. Neurodegenerative …

Short-chain fatty acids in the microbiota–gut–brain axis: role in neurodegenerative disorders and viral infections

A Majumdar, IP Siva Venkatesh… - ACS Chemical …, 2023 - ACS Publications
The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …