As with the treatment of many immune-mediated diseases, managing myositis encompasses
diverse factors, which present a challenge to the physician caring for these patients. The …

The adult and juvenile myositis syndromes, commonly referred to collectively as idiopathic
inflammatory myopathies (IIMs), are systemic autoimmune diseases with the hallmarks of …

Objective To assess the safety and efficacy of rituximab in a randomized, double‐blind,
placebo‐phase trial in adult and pediatric myositis patients. Methods Adults with refractory …

Idiopathic inflammatory myopathies (IIM) are a group of chronic, autoimmune conditions
affecting primarily the proximal muscles. The most common types are dermatomyositis (DM) …

Recently, there have been important advances in the understanding of the pathophysiologic
features, assessment, and management of patients with a newly diagnosed idiopathic …

Several uncontrolled studies have encouraged the use of rituximab (RTX) in patients with
myositis. Unfortunately, the first placebo-phase trial to assess the efficacy of RTX in …

Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by the
presence of skin lesions and inflammation of skeletal muscles; however, this feature may be …

The steadily increasing knowledge regarding pathogenetic mechanisms in autoimmune
rheumatic diseases has paved the way to different therapeutic approaches. In particular, the …

Objective. To assess clinical outcomes including imaging findings on computed tomography
(CT), pulmonary function testing (PFT), and glucocorticoid (GC) use in patients with the …

Summary Dermatomyositis (DM), polymyositis (PM), necrotizing myopathy (NM) and
inclusion body myositis (IBM) are four distinct subtypes of idiopathic inflammatory …