Recent progress in nanotechnology improving the therapeutic potential of polyphenols for cancer

IRS Vieira, L Tessaro, AKO Lima, IPS Velloso… - Nutrients, 2023 - mdpi.com
Polyphenols derived from fruits, vegetables, and plants are bioactive compounds potentially
beneficial to human health. Notably, compounds such as quercetin, curcumin …

[HTML][HTML] Application of quercetin flavonoid based hybrid nanocomposites: A review

B Parhi, D Bharatiya, SK Swain - Saudi Pharmaceutical Journal, 2020 - Elsevier
Natural bioflavonoids are an essential component of dietary supplements possessing
antimicrobial properties. Many of the bioflavonoids have resulted in positive antitumor …

Quercetin modifies 5′ CpG promoter methylation and reactivates various tumor suppressor genes by modulating epigenetic marks in human cervical cancer cells

M Kedhari Sundaram, A Hussain… - Journal of cellular …, 2019 - Wiley Online Library
The central role of epigenomic alterations in carcinogenesis has been widely
acknowledged, particularly the impact of DNA methylation on gene expression across all …

Recent advances in flavonoid-based nanocarriers as an emerging drug delivery approach for cancer chemotherapy

S Dewanjee, P Chakraborty, H Bhattacharya… - Drug Discovery …, 2023 - Elsevier
Highlights•Flavonoids exhibit therapeutic potential against different types of cancer
cells.•Poor pharmacokinetics and biopharmaceutical traits limit their therapeutic …

Magnetic UiO-66-NH2 Core–Shell Nanohybrid as a Promising Carrier for Quercetin Targeted Delivery toward Human Breast Cancer Cells

M Parsaei, K Akhbari - ACS omega, 2023 - ACS Publications
In this study, a magnetic core–shell metal–organic framework (MOF) nanocomposite, Fe3O4-
COOH@ UiO-66-NH2, was synthesized for tumor-targeting drug delivery by incorporating …

Quercetin: a potential polydynamic drug

N Georgiou, MG Kakava, EA Routsi, E Petsas… - Molecules, 2023 - mdpi.com
The study of natural products as potential drug leads has gained tremendous research
interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and …

Flavonoids nanostructures promising therapeutic efficiencies in colorectal cancer

S Hassani, H Maghsoudi, F Fattahi… - International Journal of …, 2023 - Elsevier
Colorectal cancer is among the frequently diagnosed cancers with high mortality rates
around the world. Polyphenolic compounds such as flavonoids are secondary plant …

Advances on nanoformulation approaches for delivering plant-derived antioxidants: a case of quercetin

S Rathod, S Arya, S Kanike, SA Shah… - International Journal of …, 2022 - Elsevier
Oxidative stress has been implicated in tumorigenic, cardiovascular, neuro-, and age-related
degenerative changes. Antioxidants minimize the oxidative damage through neutralization …

Nanoencapsulated dietary polyphenols for cancer prevention and treatment: successes and challenges

S Tabrez, NR Jabir, VM Adhami, MI Khan… - …, 2020 - Taylor & Francis
Many dietary polyphenols have been investigated for their therapeutic potential either as
single agents or in combinations. Despite the significant anticancer potential of these …

Inorganic nanoparticles for natural product delivery: A review

J Meena, A Gupta, R Ahuja, M Singh, S Bhaskar… - Environmental …, 2020 - Springer
The therapeutic potential of plant-based natural products is well known, yet it is actually
limited by poor water solubility, low bioavailability and rapid metabolism. These issues can …