Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications

S Laurent, D Forge, M Port, A Roch, C Robic… - Chemical …, 2008 - ACS Publications
In the past decade, the synthesis of superparamagnetic nanoparticles has been intensively
developed not only for its fundamental scientific interest but also for many technological …

Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications

AK Gupta, M Gupta - biomaterials, 2005 - Elsevier
Superparamagnetic iron oxide nanoparticles (SPION) with appropriate surface chemistry
have been widely used experimentally for numerous in vivo applications such as magnetic …

Magnetic nanoparticles for theragnostics

VI Shubayev, TR Pisanic II, S Jin - Advanced drug delivery reviews, 2009 - Elsevier
Engineered magnetic nanoparticles (MNPs) represent a cutting-edge tool in medicine
because they can be simultaneously functionalized and guided by a magnetic field. Use of …

Molecular imaging in living subjects: seeing fundamental biological processes in a new light

TF Massoud, SS Gambhir - Genes & development, 2003 - genesdev.cshlp.org
Morphological observations have driven the course of biology ever since the first
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …

Molecular imaging

R Weissleder, U Mahmood - Radiology, 2001 - pubs.rsna.org
The term molecular imaging can be broadly defined as the in vivo characterization and
measurement of biologic processes at the cellular and molecular level. In contradistinction to …

Recent advances in iron oxide nanocrystal technology for medical imaging

C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake

Y Zhang, N Kohler, M Zhang - Biomaterials, 2002 - Elsevier
Superparamagnetic magnetite nanoparticles were surface-modified with poly (ethylene
glycol)(PEG) and folic acid, respectively, to improve their intracellular uptake and ability to …

Iron oxide MR contrast agents for molecular and cellular imaging

JWM Bulte, DL Kraitchman - NMR in Biomedicine: An …, 2004 - Wiley Online Library
Molecular and cellular MR imaging is a rapidly growing field that aims to visualize targeted
macromolecules or cells in living organisms. In order to provide a different signal intensity of …

Nanotechnology: intelligent design to treat complex disease

P Couvreur, C Vauthier - Pharmaceutical research, 2006 - Springer
The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …

Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality

CC Ling, J Humm, S Larson, H Amols, Z Fuks… - International Journal of …, 2000 - Elsevier
Purpose: The goals of this study were to survey and summarize the advances in imaging
that have potential applications in radiation oncology, and to explore the concept of …