Circular RNAs play roles in regulatory networks of cell signaling pathways in human cancers

M Almouh, E Razmara, A Bitaraf, MH Ghazimoradi… - Life Sciences, 2022 - Elsevier
Abstract Aims Circular RNAs (circRNAs) are endogenous covalently closed non-coding
RNAs produced by reverse splicing of linear RNA. These molecules are highly expressed in …

[HTML][HTML] Molecular mechanisms of thyroid cancer: a competing endogenous RNA (ceRNA) point of view

Y Liu, S Khan, L Li, TLM Ten Hagen… - Biomedicine & …, 2022 - Elsevier
Thyroid cancer (TC) is the most prevalent malignancy of the endocrine system. Although
there are few treatment choices for individuals with TC, determining the underlying …

Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues

M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

Competitive endogenous RNA networks: Decoding the role of long non‐coding RNAs and circular RNAs in colorectal cancer chemoresistance

A Khalafizadeh, SD Hashemizadegan… - Journal of Cellular …, 2024 - Wiley Online Library
Colorectal cancer (CRC) is recognized as one of the most common gastrointestinal
malignancies across the globe. Despite significant progress in designing novel treatments …

PARP1 negatively regulates MAPK signaling by impairing BRAF-X1 translation

A Marranci, A Prantera, S Masotti, R De Paolo… - Journal of Hematology & …, 2023 - Springer
In human cells BRAF oncogene is invariably expressed as a mix of two coding transcripts:
BRAF-ref and BRAF-X1. These two mRNA isoforms, remarkably different in the sequence …

[HTML][HTML] Integrated analyses of an RNA binding protein-based signature related to tumor immune microenvironment and candidate drugs in osteosarcoma

AG Mohammad, D Li, R He, X Lei, L Mao… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Osteosarcoma is the most frequent primary bone malignancy, associated with
frequent recurrence and lung metastasis. RNA-binding proteins (RBPs) are pivotal in …

Association between colorectal cancer and expression levels of miR-21, miR-17-5P, miR-155 genes and the presence of Fusobacterium nucleatum in biopsy …

N Bostanshirin, B Hajikhani, AA Vaezi… - Infectious Agents and …, 2023 - Springer
Background Colorectal cancer (CRC) is considered the second-deadliest and third-most
common malignancy worldwide. Studying the carcinogenic mechanism of bacteria or their …

SMAD4 contributes to chondrocyte and osteocyte development

K Pakravan, E Razmara… - Journal of Cellular …, 2022 - Wiley Online Library
Different cellular and molecular mechanisms contribute to chondrocyte and osteocyte
development. Although vital roles of the mothers against decapentaplegic homolog 4 (also …

[HTML][HTML] LARP4A and LARP4B in cancer: The new kids on the block

JC Coleman, SR Hallett, AE Grigoriadis… - The international journal …, 2023 - Elsevier
Recent developments have mounted a stunning body of evidence underlying the
importance of RNA binding proteins (RBPs) in cancer research. In this minireview we focus …

RBM8A, a new target of TEAD4, promotes breast cancer progression by regulating IGF1R and IRS-2

F Li, X Wang, J Zhang, J Zhang, X Jing, Q Jiang… - Journal of Translational …, 2024 - Springer
Background Breast cancer (BC) is the most common malignant tumor in women worldwide,
and further elucidation of the molecular mechanisms involved in BC pathogenesis is …