Nonsense-mediated mRNA decay (NMD) is one of the best characterized and most
evolutionarily conserved cellular quality control mechanisms. Although NMD was first found …

Nonsense-mediated mRNA decay (NMD) is probably the best characterized eukaryotic RNA
degradation pathway. Through intricate steps, a set of NMD factors recognize and degrade …

Nonsense-mediated mRNA decay (NMD) is an mRNA quality-control mechanism that
typifies all eukaryotes examined to date. NMD surveys newly synthesized mRNAs and …

Although most mRNA molecules derived from protein-coding genes are destined to be
translated into functional polypeptides, some are eliminated by cellular quality control …

The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs
harboring premature termination codons (PTCs) but also regulates the abundance of a large …

Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that
monitors cytoplasmic mRNA translation and targets mRNAs undergoing premature …

Cells use messenger RNAs (mRNAs) to ensure the accurate dissemination of genetic
information encoded by DNA. Given that mRNAs largely direct the synthesis of a critical …

Nonsense-mediated mRNA decay (NMD) is arguably the best-studied eukaryotic
messenger RNA (mRNA) surveillance pathway, yet fundamental questions concerning the …

The nonsense-mediated mRNA decay (NMD) pathway is well known as a translation-
coupled quality control system that recognizes and degrades aberrant mRNAs with …

The selective degradation of mRNAs by the nonsense-mediated decay pathway is a quality
control process with important consequences for human disease. From initial studies using …