Herbal medicinal products have been documented as a significant source for discovering
new pharmaceutical molecules that have been used to treat serious diseases. Many plant …

Doxorubicin (DOX) is widely used as a broad-spectrum anti-tumor anthracycline to treat
various cancers. The serious adverse effects of DOX on cardiotoxicity limit its clinical …

Today the pharmacological possibilities of treating cancer are expanding and as a result, life
expectancy is increasing against the background of chemotherapy and supportive treatment …

Oxidative stress and inflammation play a critical role in the initiation and progression of age‐
related ocular abnormalities as cataract, glaucoma, diabetic retinopathy, and macular …

Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …

Lycopene is a lipophilic, unsaturated carotenoid, found in red-colored fruits and vegetables,
including tomatoes, watermelon, papaya, red grapefruits, and guava. The present work …

Herbal medicinal products have been documented as a significant source for discovering
new pharmaceutical molecules that have been used to treat serious diseases. Many plant …

Purpose Doxorubicin (DOX) is a highly active antineoplastic agent; however, its clinical use
is limited due to associated cardiotoxicity. This study was performed to evaluate the …

Doxorubicin (Dox) induces cardiotoxicity, thereby limiting its clinical application for
chemotherapy of cancer. The mechanism of cardiotoxicity includes the production of excess …

Oxidative stress (resulting from redox homeostasis imbalance between prooxidative and
antioxidant systems) is a major player in the pathogenesis of many inflammatory, metabolic …