Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Deciphering the role of VapBC13 and VapBC26 toxin antitoxin systems in the pathophysiology of Mycobacterium tuberculosis

A Sharma, N Singh, M Bhasin, P Tiwari… - Communications …, 2024 - nature.com
The expansion of VapBC TA systems in M. tuberculosis has been linked with its fitness and
survival upon exposure to stress conditions. Here, we have functionally characterized …

[HTML][HTML] Peptide-pulsed dendritic cells' immunomodulating effect regarding Mycobacterium tuberculosis growth in macrophages

CD Sánchez-Barinas, V Vergara-Vanegas… - Immunobiology, 2023 - Elsevier
Mycobacterium tuberculosis is one of the most successful pathogens affecting humans,
being the main cause of tuberculosis. It accounts for most infectious agent-related deaths …

Leishmania-Induced Dendritic Cell Migration and Its Potential Contribution to Parasite Dissemination

A Rebouças, TS Silva, LS Medina, BD Paredes… - Microorganisms, 2021 - mdpi.com
Leishmania, an intracellular parasite species, causes lesions on the skin and in the mucosa
and internal organs. The dissemination of infected host cells containing Leishmania is …

Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells?

CD Sánchez-Barinas, M Ocampo… - BioMed Research …, 2019 - Wiley Online Library
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, ie, the
aetiological agent); the WHO has established this disease as high priority due to its ensuing …

[PDF][PDF] 基于免疫信息学技术的结核分枝杆菌多表位疫苗构建

曹钰婷, 吴雪晗, 宁钰, 孟祥英, 乔晋娟 - 中国病原生物学杂志, 2022 - cjpb.org.cn
目的筛选具有抗原表位可能性的结核分枝杆菌高活性结合肽(HABPs), 构建基于HABPs
的多表位疫苗. 方法通过免疫信息学方法预测HABPs 的保护性抗原可能性, 细胞毒性 …

Mycobacterium tuberculosis Rv0292 Protein Peptides Could be Included in a Synthetic Anti-tuberculosis Vaccine

JA Salazar, M Ocampo, JJ Castañeda-Ramirez… - International Journal of …, 2021 - Springer
Purpose This study was aimed at characterising Mycobacterium tuberculosis (Mtb) H37Rv
Rv0292 protein peptides. As this protein forms a structural part of the cell wall and Mtb type …

Anticuerpos dirigidos contra péptidos de mycobacterium Tuberculosis y su función efectora en macrófagos y neutrófilos Infectados

DA Galeano Orjuela, JS Gómez Camargo - 2022 - 178.32.55.102
Actualmente la tuberculosis es un problema de salud pública. La forma más efectiva para
contrarrestar es la vacunación; no obstante, se cuenta con la BCG, una vacuna que no …

[PDF][PDF] Evaluación de la función efectora de linfocitos T activados por péptidos provenientes de Mycobacterium tuberculosis H37Rv en macrófagos infectados por el …

V Vergara Vanegas - 2021 - 178.32.55.102
La tuberculosis (TB) es una enfermedad infecto contagiosa, causada principalmente por
Mycobacterium tuberculosis (Mtb), la cual sigue siendo una enfermedad de alto impacto en …

Uso de células dendríticas en la generación de respuesta inmune inducida por péptidos sintéticos derivados de mycobacterium tuberculosis

CD Sánchez Barinas - repositorio.unal.edu.co
Mycobacterium tuberculosis (Mtb) es uno de los patógenos más exitosos de la humanidad,
siendo el principal causante de tuberculosis, responsable del mayor número de muertes a …