High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

[HTML][HTML] Does the food processing contaminant acrylamide cause developmental neurotoxicity? A review and identification of knowledge gaps

B Lindeman, Y Johansson, M Andreassen… - Reproductive …, 2021 - Elsevier
There is a worldwide concern on adverse health effects of dietary exposure to acrylamide
(AA) due to its presence in commonly consumed foods. AA is formed when carbohydrate …

Performance and biocompatibility of extremely tough alginate/polyacrylamide hydrogels

MC Darnell, JY Sun, M Mehta, C Johnson, PR Arany… - Biomaterials, 2013 - Elsevier
Although hydrogels now see widespread use in a host of applications, low fracture
toughness and brittleness have limited their more broad use. As a recently described …

Construction of physical-crosslink chitosan/PVA double-network hydrogel with surface mineralization for bone repair

S Bi, P Wang, S Hu, S Li, J Pang, Z Zhou, G Sun… - Carbohydrate …, 2019 - Elsevier
Weak mechanical properties, lack biocompatibility and relatively bioinert are formidable
obstruct in application of bone repair materials. Multifunctional composite materials have …

Creating stiffness gradient polyvinyl alcohol hydrogel using a simple gradual freezing–thawing method to investigate stem cell differentiation behaviors

TH Kim, DB An, SH Oh, MK Kang, HH Song, JH Lee - Biomaterials, 2015 - Elsevier
Polyvinyl alcohol (PVA) cylindrical hydrogel with a stiffness gradient was prepared using a
simple liquid nitrogen (LN 2)-contacting gradual freezing and thawing method in order to …

The toughness chitosan-PVA double network hydrogel based on alkali solution system and hydrogen bonding for tissue engineering applications

S Bi, J Pang, L Huang, M Sun, X Cheng… - International journal of …, 2020 - Elsevier
Biocompatibility and mechanical properties have always been important indicators for the
application of hydrogel materials in tissue engineering. In this work, a high strength and …

Wide-range stiffness gradient PVA/HA hydrogel to investigate stem cell differentiation behavior

SH Oh, DB An, TH Kim, JH Lee - Acta biomaterialia, 2016 - Elsevier
Although stiffness-controllable substrates have been developed to investigate the effect of
stiffness on cell behavior and function, the use of separate substrates with different degrees …

Scientific opinion on acrylamide in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2015 - Wiley Online Library
EFSA was asked to deliver a scientific opinion on acrylamide (AA) in food. AA has
widespread uses as an industrial chemical. It is also formed when certain foods are …

Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK …

I Rodríguez-Ramiro, S Ramos, L Bravo, L Goya… - The Journal of nutritional …, 2011 - Elsevier
Humans are exposed to dietary acrylamide (AA) during their lifetime; it is therefore
necessary to investigate the mechanisms associated with AA induced toxic effects …

Screening of rat mesenchymal stem cell behaviour on polydimethylsiloxane stiffness gradients

PY Wang, WB Tsai, NH Voelcker - Acta biomaterialia, 2012 - Elsevier
Substrate stiffness is emerging as an effective tool for the regulation of cell behaviours such
as locomotion, proliferation and differentiation. In order to explore the potential application of …