Abstract Sp1 (specificity protein 1) is a well-known member of a family of transcription factors
that also includes Sp2, Sp3 and Sp4, which are implicated in an ample variety of essential …

We review the rationale for the use of synthetic oleanane triterpenoids (SOs) for prevention
and treatment of disease, as well as extensive biological data on this topic resulting from …

Triterpenoids have been used for medicinal purposes in many Asian countries because of
their anti-inflammatory, antioxidant, antiproliferative, anticancer, and anticarcinogenic …

Abstract Oleanolic acid (OA, 3β-hydroxyolean-12-en-28-oic acid) is a ubiquitous pentacyclic
multifunctional triterpenoid, widely found in several dietary and medicinal plants. Natural …

Over the last two decades, extensive research on plant-based medicinal compounds has
revealed exciting and important pharmacological properties and activities of triterpenoids …

Covering: up to 2020 The transcription factor NRF2 is one of the body's major defense
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …

Pancreatic cancer (PC) remains a primary cause of cancer‐related deaths worldwide.
Existing literature has highlighted the oncogenic role of microRNA‐27a (miR‐27a) in …

Prohibitin (PHB) has been reported to play a crucial role in adipocyte differentiation and
mitochondrial function. However, the regulative mechanism of PHB during adipogenesis …

Background & Aims There has not been a broad analysis of the combined effects of altered
activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma (PDAC) cells, and it …

The human POK family members are transcription factors with a POZ domain and zinc-
fingers that act primarily as transcriptional repressors. Several members of this family are …