Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder
Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …
regarded as being in the early stages of a progressive neurodegenerative disease involving …
Neuropathology of incidental Lewy body & prodromal Parkinson's disease
T Koeglsperger, SL Rumpf, P Schließer… - Molecular …, 2023 - Springer
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder
associated with a loss of dopaminergic (DA) neurons. Despite symptomatic therapies, there …
associated with a loss of dopaminergic (DA) neurons. Despite symptomatic therapies, there …
MS‐based glycomics and glycoproteomics methods enabling isomeric characterization
Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …
Advances in mass spectrometry‐based glycomics—An update covering the period 2017–2021
The wide variety of chemical properties and biological functions found in proteins is attained
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study
Background Glycans play essential functional roles in the nervous system and their
pathobiological relevance has become increasingly recognized in numerous brain …
pathobiological relevance has become increasingly recognized in numerous brain …
MS-based glycomics: An analytical tool to assess nervous system diseases
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …
increasing due to the globe's aging population. Such diseases affect the nervous system …
Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches
Introduction Prediction of type 2 diabetes mellitus (T2DM) and its preceding factors, such as
insulin resistance (IR), is of great importance as it may allow delay or prevention of onset of …
insulin resistance (IR), is of great importance as it may allow delay or prevention of onset of …
Mass spectrometry-based qualitative and quantitative N-glycomics: An update of 2017–2018
K Xiao, Y Han, H Yang, H Lu, Z Tian - Analytica chimica acta, 2019 - Elsevier
N-glycosylation is one of the most frequently occurring protein post-translational
modifications (PTMs) with broad cellular, physiological and pathological relevance. Mass …
modifications (PTMs) with broad cellular, physiological and pathological relevance. Mass …
An Efficient and Economical N-Glycome Sample Preparation Using Acetone Precipitation
Due to the critical role of the glycome in organisms and its close connections with various
diseases, much time and effort have been dedicated to glycomics-related studies in the past …
diseases, much time and effort have been dedicated to glycomics-related studies in the past …
Isomeric separation of permethylated glycans by extra-long reversed-phase liquid chromatography (RPLC)-MS/MS
Glycosylation is known as a critical biological process that can largely affect the properties
and the functions of proteins. Glycan isomers have been shown to be involved in a variety of …
and the functions of proteins. Glycan isomers have been shown to be involved in a variety of …