Membrane transport proteins are involved in the absorption, disposition, efficacy, and/or
toxicity of many drugs. Numerous mechanisms (eg, nuclear receptors, epigenetic gene …

Cannabis has been used as a medicinal plant for thousands of years. As a result of
centuries of breeding and selection, there are now over 700 varieties of cannabis that …

SWEET sucrose transporters play important roles in the allocation of sucrose in plants.
Some SWEETs were shown to also mediate transport of the plant growth regulator …

Host shift is ecologically advantageous and a crucial driver for herbivore insect speciation.
Insects on the non-native host obtain enemy-free space and confront reduced competition …

The plasma membrane proteome resides at the interface between the extra-and intra-
cellular environment and through its various roles in signal transduction, immune …

In humans, approximately 70% of drugs are eliminated through the liver. This process is
governed by the concerted action of membrane transporters and metabolic enzymes …

Animal models are frequently used for in vitro physiologic and drug transport studies of the
colon, but there exists significant pressure to improve assay throughput as well as to achieve …

Normal substrate transport and signal transmission are the premise to ensure the health of
biological somatic cells. Therefore, a comprehensive understanding of the molecular …

Blood flow enables the delivery of oxygen and nutrients to the different tissues of the human
body. Drugs follow the same route as oxygen and nutrients; thus, drug concentrations in …

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged
trimethylammonium moiety ([H2LR] Cl, R= H, Me, Et, Ph) and four copper (II) complexes [Cu …