[HTML][HTML] Targeting super-enhancer activity for colorectal cancer therapy
IA Voutsadakis - American Journal of Translational Research, 2024 - ncbi.nlm.nih.gov
In addition to genetic variants and copy number alterations, epigenetic deregulation of
oncogenes and tumor suppressors is a major contributor in cancer development and …
oncogenes and tumor suppressors is a major contributor in cancer development and …
Utilizing deep learning models for the identification of enhancers and super-enhancers based on genomic and epigenomic features
Z Ahani, M Shahiki Tash… - Journal of Intelligent …, 2024 - content.iospress.com
Super-enhancers are a category of active super-enhancers densely occupied by
transcription factors and chromatin regulators, controlling the expression of disease-related …
transcription factors and chromatin regulators, controlling the expression of disease-related …
The Role of SARS-CoV-2 Spike Protein in Long-term Damage of Tissues and Organs, the Underestimated Role of Retrotransposons and Stem Cells, a Working …
MG Balzanelli, R Rastmanesh, P Distratis… - … Metabolic & Immune …, 2025 - benthamdirect.com
Coronavirus disease-2019 (COVID-19) is a respiratory disease in which Spike protein from
SARS-CoV-2 plays a key role in transferring virus genomic code into target cells. Spike …
SARS-CoV-2 plays a key role in transferring virus genomic code into target cells. Spike …
The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation
Y Yang, Q Li, X Liu, C Shao, H Yang, S Niu… - Frontiers in …, 2024 - frontiersin.org
Background Studies have shown that DNA methylation of the CACNA1C gene is involved in
the pathogenesis of various diseases and the mechanism of drug action. However, its …
the pathogenesis of various diseases and the mechanism of drug action. However, its …
[HTML][HTML] Enhancers and super-enhancers as master regulators in cancer
P Sarvari, P Sarvari, I Ramirez-Diaz… - INNOSC Theranostics …, 2024 - accscience.com
Gene expression regulation is one of the most fundamental cellular processes, enabling the
activation of a gene to produce either the translatable protein-coding transcript (mRNA) or a …
activation of a gene to produce either the translatable protein-coding transcript (mRNA) or a …
Fluorescently controlled investigation of super-enhancers with CRISPR interference and CRISPR prime editing systems
In the evolving landscape of genomic research, our study delves into the intricate
exploration of super-enhancers, pivotal and controversial elements exerting profound …
exploration of super-enhancers, pivotal and controversial elements exerting profound …
Genetically Engineered Nanocapsules with Fluorescent and Magnetic Markers for Cell Tracking and Targeted Drug Delivery
AN Gabashvili, DD Namestnikova… - … Laser Optics (ICLO), 2024 - ieeexplore.ieee.org
Different functionalized nanocarriers are currently being intensively studied for various
theranostic applications. Joining the approaches of genetic and chemical engineering novel …
theranostic applications. Joining the approaches of genetic and chemical engineering novel …