Direct access to hydrazides and amides from carboxylic acids via acyloxyphosphonium ion
Adding an amine moiety to a carbonyl group poses a challenging synthetic task;
nevertheless, it is a crucial step in developing numerous bioactive molecules. Here, we …
nevertheless, it is a crucial step in developing numerous bioactive molecules. Here, we …
Metal-Free Switchable Chemo-and Regioselective Alkylation of Oxindoles Using Secondary Alcohols
In this study, we have disclosed N-alkylation and C-alkylation reactions of 2-oxindoles with
secondary alcohols. Interestingly, these chemoselective reactions are tunable by changing …
secondary alcohols. Interestingly, these chemoselective reactions are tunable by changing …
Halogen Promoted Desulfurative Cleavage of Cyclopropylmethyl Thioethers and Amination of the Formed Cyclopropylcarbinyl Cations
P Marín‐Díaz, C Martínez‐Núñez… - European Journal of …, 2024 - Wiley Online Library
Cyclopropylmethyl sulfides react with N‐fluorosulfonimide (NFSI) or molecular iodine,
enabling C− S cleavage to generate cyclopropylcarbinyl cations, which evolve through …
enabling C− S cleavage to generate cyclopropylcarbinyl cations, which evolve through …
Brønsted Acid‐Catalyzed Regioselective Coupling between Azoles and Arylcyclobutenes
C Jing, J Wang, J Chang, Y He, Z Zheng… - Chemistry–An Asian … - Wiley Online Library
Herein, we describe a protocol for Brønsted acid‐catalyzed regioselective coupling of azoles
such as pyrazoles, 1, 2, 3‐triazole, 1, 3, 4‐triazole, benzotriazole, indazole and tetrazole, to …
such as pyrazoles, 1, 2, 3‐triazole, 1, 3, 4‐triazole, benzotriazole, indazole and tetrazole, to …