Structure and interaction of nanoparticle–protein complexes

S Kumar, I Yadav, VK Aswal, J Kohlbrecher - Langmuir, 2018 - ACS Publications
The integration of nanoparticles with proteins is of high scientific interest due to the amazing
potential displayed by their complexes, combining the nanoscale properties of nanoparticles …

Protein purification with nanoparticle-enhanced crystallisation

W Chen, TNH Cheng, LF Khaw, X Li, H Yang… - Separation and …, 2021 - Elsevier
In this study, silica nanoparticle was synthesised and used to promote lysozyme
crystallisation effectively against high concentrations of protein impurity (bovine serum …

Comparative evaluations of bulk seeded protein crystallization in batch versus continuous slug flow crystallizers

S Pu, K Hadinoto - Chemical Engineering Research and Design, 2021 - Elsevier
The present work evaluated for the first time the use of continuous slug flow crystallizer
(CSFC) in bulk seeded protein crystallization, using lysozyme (LYZ) as the model protein …

Towards an enhanced control of protein crystallization: Seeded batch lysozyme crystallization in a meso oscillatory flow reactor

F Castro, I Cunha, A Ferreira, JA Teixeira… - … Research and Design, 2022 - Elsevier
Protein crystallization has been shown as a viable alternative to conventional protein
purification methods. However, the stochastic and spontaneous nature of the primary …

Digital Design of an Agrochemical Crystallization Process via Two-Dimensional Population Balance Modeling

WL Wu, C Chappelow, N Hanspal… - … Process Research & …, 2024 - ACS Publications
Solution crystallization is commonly used in the agrochemical industry to isolate and purify
the active ingredient (AI). The generated particles' characteristics, typically needle-like …

Self-assembly of magnetic lysozyme crystals with a medium of polymers

Q Zhang, M Su, L Yu, Y Zhang - Crystal Growth & Design, 2021 - ACS Publications
Bulk protein crystallization used in biopharming as an alternative method of protein-based
biotherapeutics purification has been researched with a noticeable focus because of its …

Optimization on crystallization process of the magnetic core lysozyme

L Hou, C Qu, M Su, Z Liang, Q Hao - Particuology, 2024 - Elsevier
The continuous growth of the biomedical market highlights the significance of improvement
in the efficiency of batch production for protein drug crystals. Herein, we investigated the …

[HTML][HTML] Process modelling of protein crystallisation: A case study of lysozyme

HM Mitchell, D Jovannus, I Rosbottom, FJ Link… - … Research and Design, 2023 - Elsevier
With the rise in interest of protein crystallisation as a purification step in downstream
processing, there is significant interest in the process modelling of these crystallisation …

Hen egg lysozyme polymorphs mediated by two ionic liquids during batch cooling crystallization

S Jia, S Wang, J Yang, N Li, Z Wang - Journal of the Indian Chemical …, 2024 - Elsevier
Lysozyme batch cooling crystallization in the presence of two ionic liquids (ILs), 1-butyl-3-
methylimidazolium chloride ([C 4 mim] Cl), and 1, 3-dimethylimidazolium iodide ([C 1 mim] I) …

Exploring the effects and mechanisms of carbon nanomaterial diversity on the morphology of lysozyme crystals

X Li, H Wang, X Kuang, J Ma, X Feng - CrystEngComm, 2017 - pubs.rsc.org
Carbon nanomaterials (CNMs) provide various surface charges, structural characteristics
and energy features for nano-engineering applications, but the effects of CNMs on …