The multifaceted biology of plasmacytoid dendritic cells
M Swiecki, M Colonna - Nature Reviews Immunology, 2015 - nature.com
Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation
T Möröy, L Vassen, B Wilkes… - Blood, The Journal of …, 2015 - ashpublications.org
The DNA-binding zinc finger transcription factors Gfi1 and Gfi1b were discovered more than
20 years ago and are recognized today as major regulators of both early hematopoiesis and …
20 years ago and are recognized today as major regulators of both early hematopoiesis and …
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage
Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …
Multifaceted actions of GFI1 and GFI1B in hematopoietic stem cell self-renewal and lineage commitment
H Beauchemin, T Möröy - Frontiers in Genetics, 2020 - frontiersin.org
Growth factor independence 1 (GFI1) and the closely related protein GFI1B are small
nuclear proteins that act as DNA binding transcriptional repressors. Both recognize the …
nuclear proteins that act as DNA binding transcriptional repressors. Both recognize the …
The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response
J Fraszczak, T Möröy - Advances in immunology, 2021 - Elsevier
Abstract GFI1 and GFI1B are small nuclear proteins of 45 and 37 kDa, respectively, that
have a simple two-domain structure: The first consists of a group of six c-terminal C 2 H 2 …
have a simple two-domain structure: The first consists of a group of six c-terminal C 2 H 2 …
Exploring the relationships between amphibian (Xenopus laevis) myeloid cell subsets
A Yaparla, DV Koubourli, M Popovic… - Developmental & …, 2020 - Elsevier
The differentiation of distinct leukocyte subsets is governed by lineage-specific growth
factors that elicit disparate expression of transcription factors and markers by the developing …
factors that elicit disparate expression of transcription factors and markers by the developing …