Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is
chemotherapy, but the prognosis remains poor. Camrelizumab (an anti–programmed death …

Background The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease-
dependent manner in responses to variety of stresses that are common in cancers. We focus …

Background Programmed cell death 1 (PD-1) blockade induces tumor regression in patients
with advanced esophageal squamous cell carcinoma (ESCC); however, little is known about …

Esophageal cancer is one of the most aggressive gastrointestinal cancers. This review
focuses on eight topics within the multidisciplinary approach for esophageal cancer. As …

Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

Esophageal cancer (EC) is one of the most common cancers with high morbidity and
mortality rates. EC includes two histological subtypes, namely esophageal squamous cell …

There are limited published data on recent cancer incidence and mortality trends worldwide.
We used the International Agency for Research on Cancer's CANCER Mondial …

Importance Effective treatment options are limited for patients with advanced, metastatic
esophageal cancer progressing after 2 or more lines of systemic therapy. Objective To …