Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …

The role of the gut microbiota in human health is one of the most important research topics.
There is a strong relationship between the microbiota-gut-brain axis and cognitive functions …

Many physical, social, and psychological changes occur during aging that raise the risk of
developing chronic diseases, frailty, and dependency. These changes adversely affect the …

The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

The gut mucosa of human is covered by mucus, functioning as a crucial defense line for the
intestine against external stimuli and pathogens. Mucin2 (MUC2) is a subtype of secretory …

Although recent studies have revealed the association between the human microbiome
especially gut microbiota and longevity, their causality remains unclear. Here, we assess the …

The prevalence of type 2 diabetes (T2D) is increasing worldwide, with many patients
developing long-term complications that affect their cardiovascular, urinary, alimentary, and …

Abstract Frailty and Biological Age are two closely related concepts; however, frailty is a
multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a …

This observational study aimed to investigate associations between dietary live microbe
intake and mortality, as well as biological aging. Adults from the 1999–2018 National Health …

Akkermansia muciniphila (A. muciniphila) is an anaerobic bacterium that widely colonizes
the mucus layer of the human and animal gut. The role of this symbiotic bacterium in host …