The hypothalamic paraventricular nucleus (PVN) is the primary driver of hypothalamo–
pituitary–adrenocortical (HPA) responses. At least part of the role of the PVN is managing …

The past 20 years witnessed an enormous leap in understanding of the central regulation of
whole-body energy metabolism. Genetic tools have enabled identification of the region …

Significant advancements have been made in the past century regarding the neuronal
control of feeding behavior and energy expenditure. The effects and mechanisms of action …

Glial cells actively participate in synaptic transmission. They clear molecules from the
synaptic cleft, receive signals from neurons and, in turn, release molecules that can …

▪ Abstract Physiological activation of the magnocellular hypothalamo-neurohypophysial
system induces a coordinated astrocytic withdrawal from between the magnocellular somata …

Afferent activity can induce fast, feed-forward changes in synaptic efficacy that are synapse
specific. Using combined electrophysiology, caged molecule photolysis, and Ca 2+ imaging …

Oxytocin-secreting neurons of the hypothalamoneurohypophysial system undergo
reversible morphological changes whenever they are strongly stimulated. In the …

Chronic stress precipitates pronounced enhancement of central stress excitability, marked
by sensitization of hypothalamic‐pituitary‐adrenocortical (HPA) axis responses and …

The past decade has witnessed dramatic advancements regarding the neuroendocrine
control of food intake and energy homeostasis and the effects of peripheral metabolic …

Exogenous cannabinoids have been shown to significantly alter neuroendocrine output,
presaging the emergence of endogenous cannabinoids as important signalling molecules in …