[HTML][HTML] miRNA-based biomarkers, therapies, and resistance in Cancer

B He, Z Zhao, Q Cai, Y Zhang, P Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …

[HTML][HTML] Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer

MA Diamantopoulos, P Tsiakanikas… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …

MicroRNA in leukemia: Tumor suppressors and oncogenes with prognostic potential

R Mardani, MH Jafari Najaf Abadi… - Journal of cellular …, 2019 - Wiley Online Library
Leukemia is known as a progressive malignant disease, which destroys the blood‐forming
organs and results in adverse effects on the proliferation and development of leukocytes and …

The diagnostic and prognostic value of miR-155 in cancers: an updated meta-analysis

Y Wu, Q Hong, F Lu, Z Zhang, J Li, Z Nie… - Molecular Diagnosis & …, 2023 - Springer
Background MicroRNA-155 has been discussed as a biomarker in cancer diagnosis and
prognosis. Although relevant studies have been published, the role of microRNA-155 …

MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia

K Katsaraki, P Karousi, PI Artemaki, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …

MiR-155-targeted IcosL controls tumor rejection

E Tili, H Otsu, TL Commisso, A Palamarchuk… - Proceedings of the …, 2024 - pnas.org
Elevated levels of miR-155 in solid and liquid malignancies correlate with aggressiveness of
the disease. In this manuscript, we show that miR-155 targets transcripts encoding IcosL, the …

A novel, mitochondrial, internal tRNA-derived RNA fragment possesses clinical utility as a molecular prognostic biomarker in chronic lymphocytic leukemia

P Karousi, PG Adamopoulos, SG Papageorgiou… - Clinical …, 2020 - Elsevier
Objectives Chronic lymphocytic leukemia (CLL) is the most common leukemia among
adults. The prognosis of CLL patients varies considerably. Transfer RNA-derived RNA …

Abnormal Expression of BTLA and CTLA‐4 Immune Checkpoint Molecules in Chronic Lymphocytic Leukemia Patients

L Karabon, A Partyka, L Ciszak… - Journal of …, 2020 - Wiley Online Library
Chronic lymphocytic leukemia (CLL) is characterized by the peripheral accumulation of
neoplastic B cells and is frequently complicated by the systemic immunosuppression …

Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia

A Rzepiel, N Kutszegi, A Gézsi, JC Sági… - Journal of translational …, 2019 - Springer
Background Treatment stratification based on bone marrow minimal residual disease (MRD)
at set time points has resulted in considerably improved survival in pediatric acute …

Identification of a novel, internal tRNA-derived RNA fragment as a new prognostic and screening biomarker in chronic lymphocytic leukemia, using an innovative …

K Katsaraki, PI Artemaki, SG Papageorgiou, V Pappa… - Leukemia Research, 2019 - Elsevier
Chronic lymphocytic leukemia (CLL) is one of the most common types of leukemia in adults.
Several studies have identified various prognostic biomarkers in CLL. In this study, we …