A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships

BJ Houston, A Riera-Escamilla… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Human male infertility has a notable genetic component, including well-
established diagnoses such as Klinefelter syndrome, Y-chromosome microdeletions and …

Understanding the genetics of human infertility

Q Sang, PF Ray, L Wang - Science, 2023 - science.org
Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities

CLR Barratt, L Björndahl, CJ De Jonge… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Herein, we describe the consensus guideline methodology, summarize the
evidence-based recommendations we provided to the World Health Organization (WHO) for …

[HTML][HTML] Male oxidative stress infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic male infertility

A Agarwal, N Parekh, MKP Selvam… - The world journal of …, 2019 - synapse.koreamed.org
Despite advances in the field of male reproductive health, idiopathic male infertility, in which
a man has altered semen characteristics without an identifiable cause and there is no …

Sexual dysfunction and male infertility

F Lotti, M Maggi - Nature Reviews Urology, 2018 - nature.com
Infertility affects up to 12% of all men, and sexual dysfunction occurs frequently in men of
reproductive age, causing infertility in some instances. In infertile men, hypoactive sexual …

[HTML][HTML] Functional and taxonomic dysbiosis of the gut, urine, and semen microbiomes in male infertility

SD Lundy, N Sangwan, NV Parekh, MKP Selvam… - European urology, 2021 - Elsevier
Background Little is known about the role of the genitourinary and gastrointestinal
microbiota in the pathogenesis of male infertility. Objective To compare the taxonomic and …

Disorders of spermatogenesis: perspectives for novel genetic diagnostics after 20 years of unchanged routine

F Tüttelmann, C Ruckert, A Röpke - Medizinische Genetik, 2018 - degruyter.com
Infertility is a common condition estimated to affect 10–15% of couples. The clinical causes
are attributed in equal parts to the male and female partners. Diagnosing male infertility …

Infectious, inflammatory and 'autoimmune'male factor infertility: how do rodent models inform clinical practice?

M Fijak, A Pilatz, MP Hedger, N Nicolas… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Infection and inflammation of the reproductive tract are significant causes of
male factor infertility. Ascending infections caused by sexually transmitted bacteria or urinary …

Male infertility

A Agarwal, S Baskaran, N Parekh, CL Cho, R Henkel… - The Lancet, 2021 - thelancet.com
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

European Academy of Andrology guideline Management of oligo‐astheno‐teratozoospermia

GM Colpi, S Francavilla, G Haidl, K Link, HM Behre… - …, 2018 - Wiley Online Library
Background Oligo‐astheno‐teratozoospermia is frequently reported in men from infertile
couples. Its etiology remains, in the majority of cases, unknown with a variety of factors to …