Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Development of ion chemosensors based on porphyrin analogues

Y Ding, WH Zhu, Y Xie - Chemical Reviews, 2017 - ACS Publications
Sensing of metal ions and anions is of great importance because of their widespread
distribution in environmental systems and biological processes. Colorimetric and fluorescent …

Molecular magnetic resonance imaging with Gd (III)-based contrast agents: challenges and key advances

H Li, TJ Meade - Journal of the American Chemical Society, 2019 - ACS Publications
In an era of personalized medicine, the clinical community has become increasingly focused
on understanding diseases at the cellular and molecular levels. Magnetic resonance …

Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance

Z Ge, S Liu - Chemical Society Reviews, 2013 - pubs.rsc.org
Self-assembled nanostructures of amphiphilic and double hydrophilic block copolymers
have been increasingly utilized as potent polymeric nanocarriers of therapeutic drugs …

Emerging applications of porphyrins and metalloporphyrins in biomedicine and diagnostic magnetic resonance imaging

M Imran, M Ramzan, AK Qureshi, MA Khan, M Tariq - Biosensors, 2018 - mdpi.com
In recent years, scientific advancements have constantly increased at a significant rate in the
field of biomedical science. Keeping this in view, the application of porphyrins and …

Fluorescent and colorimetric ion probes based on conjugated oligopyrroles

Y Ding, Y Tang, W Zhu, Y Xie - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal ions and anions play important roles in many industrial and biochemical processes,
and thus it is highly desired to detect them in the relevant systems. Small organic molecule …

Phosphorescent chemosensors based on heavy-metal complexes

Q Zhao, F Li, C Huang - Chemical Society Reviews, 2010 - pubs.rsc.org
Recently, the use of phosphorescent heavy-metal complexes as chemosensors has
attracted increasing interest due to their advantageous photophysical properties. This critical …

Near-infrared fluorescence: application to in vivo molecular imaging

SA Hilderbrand, R Weissleder - Current opinion in chemical biology, 2010 - Elsevier
Molecular imaging often relies on the use of targeted and activatable reporters to quantitate
and visualize targets, biological processes, and cells in vivo. The use of optical probes with …

Application of metal coordination chemistry to explore and manipulate cell biology

KL Haas, KJ Franz - Chemical reviews, 2009 - ACS Publications
Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

Multimodality imaging probes: design and challenges

A Louie - Chemical reviews, 2010 - ACS Publications
The conundrum of modality selection in clinical diagnostic imaging is that modalities with the
highest sensitivity have relatively poor resolution, while those with high resolution have …