An update on repeated blast traumatic brain injury

AR Ravula, T Das, A Gosain, T Dolalas, S Padhi… - Current Opinion in …, 2022 - Elsevier
Abstract Service members and law enforcement experience repeated blast exposures
frequently due to the constant use of heavy weaponry, including large caliber rifles and …

A comprehensive review of experimental rodent models of repeated blast TBI

M Skotak, MT Townsend, KV Ramarao… - Frontiers in …, 2019 - frontiersin.org
We reviewed the relevant literature delineating advances in the development of the
experimental models of repeated blast TBI (rbTBI). It appears this subject is a relatively …

Neurotrauma biomarker levels and adverse symptoms among military and law enforcement personnel exposed to occupational overpressure without diagnosed …

AM Boutté, B Thangavelu, J Nemes… - JAMA Network …, 2021 - jamanetwork.com
Importance There is a scientific and operational need to define objective measures of
exposure to low-level overpressure (LLOP) and concussion-like symptoms among persons …

Animal model of repeated low-level blast traumatic brain injury displays acute and chronic neurobehavioral and neuropathological changes

AR Ravula, J Rodriguez, D Younger, V Perumal… - Experimental …, 2022 - Elsevier
Blast-induced neurotrauma (BINT) is not only a signature injury to soldiers in combat field
and training facilities but may also a growing concern in civilian population due to recent …

Repeated occupational exposure to low-level blast in the Canadian armed forces: effects on hearing, balance, and ataxia

A Nakashima, O Vartanian, SG Rhind, K King… - Military …, 2022 - academic.oup.com
Introduction Recently, there has been increasing concern about the adverse health effects of
long-term occupational exposure to low-level blast in military personnel. Occupational blast …

Dynamic monitoring of service members to quantify blast exposure levels during combat training using BlackBox Biometrics Blast Gauges: explosive breaching …

S Wiri, T Massow, J Reid, J Whitty, C Dunbar… - Frontiers in …, 2023 - frontiersin.org
CONQUER is a pilot blast monitoring program that monitors, quantifies, and reports to
military units the training-related blast overpressure exposure of their service members …

MCC950 attenuates microglial NLRP3-mediated chronic neuroinflammation and memory impairment in a rat model of repeated low-level blast exposure

AR Ravula, KE Murray, KVR Rao, BJ Pfister… - Journal of …, 2024 - liebertpub.com
Blast-induced traumatic brain injury is typically regarded as a signature medical concern for
military personnel who are exposed to explosive devices in active combat zones. However …

Repetitive low-level blast exposure and neurocognitive effects in army ranger mortarmen

JLA Woodall, JA Sak, KR Cowdrick… - Military …, 2023 - academic.oup.com
Introduction Occupational exposure to repetitive, low-level blasts in military training and
combat has been tied to subconcussive injury and poor health outcomes for service …

Partial depletion of microglia attenuates long-term potentiation deficits following repeated blast traumatic brain injury in organotypic hippocampal slice cultures

N Varghese, B Morrison III - Journal of Neurotrauma, 2023 - liebertpub.com
Blast-induced traumatic brain injury (bTBI) has been a health concern in both military and
civilian populations due to recent military and geopolitical conflicts. Military service members …

Overpressure exposure from. 50-caliber rifle training is associated with increased amyloid beta peptides in serum

B Thangavelu, CR LaValle, MJ Egnoto… - Frontiers in …, 2020 - frontiersin.org
Background: Overpressure (OP) is an increase in air pressure above normal atmospheric
levels. Military personnel are repeatedly exposed to low levels of OP caused by various …