Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

V Cottin, NA Hirani, DL Hotchkin… - European …, 2018 - Eur Respiratory Soc
Although these conditions are rare, a proportion of patients with interstitial lung diseases
(ILDs) may develop a progressive-fibrosing phenotype. Progressive fibrosis is associated …

Tobacco smoking and risk for pulmonary fibrosis: a prospective cohort study from the UK Biobank

V Bellou, L Belbasis, E Evangelou - Chest, 2021 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease of unknown
origin. A limited number of small studies show an effect of tobacco smoking on risk of IPF …

Healthcare utilisation and costs in the diagnosis and treatment of progressive-fibrosing interstitial lung diseases

C Holtze, K Flaherty, M Kreuter, F Luppi… - European …, 2018 - Eur Respiratory Soc
There are over 200 interstitial lung diseases (ILDs). In addition to patients with idiopathic
pulmonary fibrosis (IPF), a percentage of patients with other ILDs also develop progressive …

Pro-fibrotic effects of CCL18 on human lung fibroblasts are mediated via CCR6

K Höhne, A Wagenknecht, C Maier, P Engelhard… - Cells, 2024 - mdpi.com
Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown origin,
with a median patient survival time of~ 3 years after diagnosis without anti-fibrotic therapy. It …

[HTML][HTML] Proteomic analysis reveals key proteins in extracellular vesicles cargo associated with idiopathic pulmonary fibrosis in vitro

JM Velázquez-Enríquez, JC Santos-Álvarez… - Biomedicines, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, and highly fatal
disease. It is characterized by the increased activation of both fibroblast and myofibroblast …

Hypercalciuria in sarcoidosis: a specific biomarker with clinical utility

P Cameli, C Caffarelli, RM Refini, L Bergantini… - Frontiers in …, 2020 - frontiersin.org
Background: Changes in calcium metabolism are quite common in sarcoidosis:
hypercalciuria is linked to a persistent clinical phenotype and more active disease. No data …

Ground glass and fibrotic change in children with surfactant protein C dysfunction mutations

EM DeBoer, DR Liptzin, SM Humphries… - Pediatric …, 2021 - Wiley Online Library
Introduction Therapeutics exist to treat fibrotic lung disease in adults, but these have not
been investigated in children. Defining biomarkers for pediatric fibrotic lung disease in …

Idiopathic pulmonary fibrosis: educational needs of health-care providers, patients, and caregivers

D Ramadurai, S Corder, T Churney… - Chronic Respiratory …, 2019 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with poor quality of
life. Debilitating symptoms and the reality of shortened survival impact patients' physical and …

[HTML][HTML] Conventional and multi-omics assessments of subacute inhalation toxicity due to propylene glycol and vegetable glycerin aerosol produced by electronic …

M Chu, R Wang, X Jing, D Li, G Fu, J Deng, Z Xu… - Ecotoxicology and …, 2024 - Elsevier
Propylene glycol (PG) and vegetable glycerin (VG) are the most common solvents used in
electronic cigarette liquids. No long-term inhalation toxicity assessments have been …

Discrimination between NSIP-and IPF-derived fibroblasts based on multi-parameter characterization of their growth, morphology and physic-chemical properties

B Orzechowska, K Awsiuk, D Wnuk, J Pabijan… - International Journal of …, 2022 - mdpi.com
Background: The aim of the research presented here was to find a set of parameters
enabling discrimination between three types of fibroblasts, ie, healthy ones and those …