Gene transcription is the process by which the genetic codes of organisms are read and
interpreted as a set of instructions for cells to divide, differentiate, migrate, and mature. As …

Over the past 4 years, nearly 100 exome sequencing studies have revealed the high
frequency of mutations in the genes encoding the subunits of ATP-dependent chromatin …

Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

During the last decade, a host of epigenetic mechanisms were found to contribute to cancer
and other human diseases. Several genomic studies have revealed that∼ 20% of …

The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …

Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …

Research over the past several decades has provided insight into the processes that govern
early brain development and how those processes contribute to behavior. In the following …

Activity-dependent plasticity of vertebrate neurons allows the brain to respond to its
environment. During brain development, both spontaneous and sensory-driven neural …

Sensory experience and the resulting synaptic activity within the brain are critical for the
proper development of neural circuits. Experience-driven synaptic activity causes membrane …