Nonreplicative functions of the origin recognition complex
VV Popova, AV Brechalov, SG Georgieva… - Nucleus, 2018 - Taylor & Francis
Origin recognition complex (ORC), a heteromeric six-subunit complex, is the central
component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and …
component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and …
Destabilization of the replication fork protection complex disrupts meiotic chromosome segregation
W Escorcia, SL Forsburg - Molecular Biology of the Cell, 2017 - Am Soc Cell Biol
The replication fork protection complex (FPC) coordinates multiple processes that are crucial
for unimpeded passage of the replisome through various barriers and difficult to replicate …
for unimpeded passage of the replisome through various barriers and difficult to replicate …
Deletion of Orc4 during oogenesis severely reduces polar body extrusion and blocks zygotic DNA replication
H Nguyen, H Wu, A Ung, Y Yamazaki… - Biology of …, 2022 - academic.oup.com
Origin recognition complex subunit 4 (ORC4) is a DNA-binding protein required for DNA
replication. During oocyte maturation, after the last oocyte DNA replication step and before …
replication. During oocyte maturation, after the last oocyte DNA replication step and before …
The role of ORC4 in enucleation of murine erythroleukemia (MEL) cells is similar to that in oocyte polar body extrusion
H Nguyen, A Ung, WS Ward - Systems biology in reproductive …, 2020 - Taylor & Francis
ABSTRACT The Origin Replication Complex subunit 4 (ORC4) is one in six subunits of the
Origin Replication Complexes (ORCs) which is essential for initiating licensing at DNA …
Origin Replication Complexes (ORCs) which is essential for initiating licensing at DNA …
Spatial and temporal resolution of mORC4 fluorescent variants reveals structural requirements for achieving higher order self-association and pronuclei entry
H Nguyen, WS Ward, NG James - Methods and applications in …, 2019 - iopscience.iop.org
Abstract The Origin Replication Complex (ORC), which is a multi-subunit protein complex
composed of six proteins ORC1–6, is essential for initiating licensing at DNA replication …
composed of six proteins ORC1–6, is essential for initiating licensing at DNA replication …
The Role of N-WASP in ORC4 Mediated Polar Body Extrusion
DCO Elento - 2020 - search.proquest.com
Oocyte meiosis is completed though two asymmetric cellular divisions, where the oocyte
extrudes half of its DNA two times, into two smaller daughter cells called polar bodies. N …
extrudes half of its DNA two times, into two smaller daughter cells called polar bodies. N …
The Licensing Protein ORC4 is Required for Polar Body Extrusion During Murine Meiosis.
HT Nguyen - 2017 - scholarspace.manoa.hawaii.edu
Abstract Six proteins, ORC1-6, make up the origin recognition complex (ORC) that initiates
licensing of the DNA replication origin. We have previously shown that subunit ORC1 …
licensing of the DNA replication origin. We have previously shown that subunit ORC1 …