Functional interfaces, biological pathways, and regulations of interferon-related DNA damage resistance signature (IRDS) genes

M Padariya, A Sznarkowska, S Kote, M Gómez-Herranz… - Biomolecules, 2021 - mdpi.com
Interferon (IFN)-related DNA damage resistant signature (IRDS) genes are a subgroup of
interferon-stimulated genes (ISGs) found upregulated in different cancer types, which …

In-cell labeling and mass spectrometry for systems-level structural biology

JD Chavez, HH Wippel, X Tang, A Keller… - Chemical …, 2021 - ACS Publications
Biological systems have evolved to utilize proteins to accomplish nearly all functional roles
needed to sustain life. A majority of biological functions occur within the crowded …

Immunoaffinity capillary electrophoresis in the era of proteoforms, liquid biopsy and preventive medicine: a potential impact in the diagnosis and monitoring of disease …

NA Guzman, DE Guzman - Biomolecules, 2021 - mdpi.com
Over the years, multiple biomarkers have been used to aid in disease screening, diagnosis,
prognosis, and response to therapy. As of late, protein biomarkers are gaining strength in …

Mass Spectrometry for Assessing Protein–Nucleic Acid Interactions

X He, X Chen, Y Wang - Analytical chemistry, 2023 - ACS Publications
Protein− nucleic acid interactions, including the interac-tions of proteins with DNA, RNA, and
DNA/RNA hybrid, often confer important biological consequences to targeted nucleic acids …

Metal–Organic Framework Induced Stabilization of Proteins in Polymeric Nanoparticles

MRH Khan, Z Armstrong, M Lenertz… - … Applied Materials & …, 2024 - ACS Publications
Developing protein confinement platforms is an attractive research area that not only
promotes protein delivery but also can result in artificial environment mimicking of the …

Mass Spectrometry Advances in Analysis of Glioblastoma

S Al Shboul, A Singh, R Kobetic… - Mass spectrometry …, 2024 - Wiley Online Library
Some cancers such as glioblastoma (GBM), show minimal response to medical
interventions, often only capable of mitigating tumor growth or alleviating symptoms. High …

The Quantitative Biotinylproteomics Studies Reveal a WInd-Related Kinase 1 (Raf-Like Kinase 36) Functioning as an Early Signaling Component in Wind-Induced …

N Yang, J Ren, S Dai, K Wang, M Leung, Y Lu… - Molecular & Cellular …, 2024 - ASBMB
Wind is one of the most prevalent environmental forces entraining plants to develop various
mechano-responses, collectively called thigmomorphogenesis. Largely unknown is how …

[HTML][HTML] Insights into Transient Dimerization of Carnitine/Acylcarnitine Carrier (SLC25A20) from Sarkosyl/PAGE, Cross-Linking Reagents, and Comparative Modelling …

N Giangregorio, A Tonazzi, CL Pierri, C Indiveri - Biomolecules, 2024 - mdpi.com
The carnitine/acylcarnitine carrier (CAC) is a crucial protein for cellular energy metabolism,
facilitating the exchange of acylcarnitines and free carnitine across the mitochondrial …

In Vitro Cross-Linking MS Reveals SMG1–UPF2–SMG7 Assembly as Molecular Partners within the NMD Surveillance

M Padariya, B Vojtesek, T Hupp… - International Journal of …, 2024 - mdpi.com
mRNAs containing premature stop codons are responsible for various genetic diseases as
well as cancers. The truncated proteins synthesized from these aberrant mRNAs are seldom …

Probing the structures of G protein-coupled receptors with mass spectrometry-based techniques

C Pan, J Li, S Yuan, W Shui - International Journal of Mass Spectrometry, 2023 - Elsevier
G protein-coupled receptors (GPCRs) are key molecules to regulate numerous physiological
processes in the human body, and represent one of the largest protein families as targets for …