Molecular syntheses largely rely on time‐and labour‐intensive prefunctionalization
strategies. In contrast, C− H activation represents an increasingly powerful approach that …

The metal-catalyzed asymmetric conjugate addition (ACA) reaction has emerged as a
general and powerful approach for the construction of optically active compounds and is …

This Feature Article presents and discusses the use of different methods to quantify and
explore the steric impact of N-heterocyclic carbene (NHC) ligands. These include (a) the …

A catalytic asymmetric conjugate hydrophosphination of α, β-unsaturated amides is
accomplished by virtue of the strong nucleophilicity of copper (I)-PPh2 species, which …

N-Heterocyclic carbenes (NHCs) are defined as singlet carbenes, in which the divalent
carbenic center is connected directly to at least one nitrogen atom within the heterocycle. 1 …

Presented is the first enantioselective copper‐catalyzed 1, 6‐conjugate addition of bis
(pinacolato) diboron to para‐quinone methides. The reaction proceeds with excellent yields …

Annulated pyridones are an important scaffold found in many biologically active compounds.
A Ni (0)-catalyzed C–H functionalization of 2-and 4-pyridones is disclosed, providing access …

Boron compounds have been traditionally regarded as “Lewis acids” preferring to accept
electrons rather than donate them in the course of their reactions but current examples of …

The first broadly applicable metal-free enantioselective method for boron conjugate addition
(BCA) to α, β-unsaturated carbonyls is presented. The C–B bond forming reactions are …

Abstract The 1, 6‐annulated 2‐pyridone motif is found in many biologically active
compounds and its close relation to the indolizidine and quinolizidine alkaloid core makes it …