Excited (triplet) states offer a myriad of attractive synthetic pathways, including
cycloadditions, selective homolytic bond cleavages and strain-release chemistry …

Sulfur (VI)‐fluoride exchange linkage as a next generation of click chemistry was introduced
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …

Highly strained 1, 3-disubstituted bicyclo [1.1. 1] pentanes (BCPs) have been established as
bioisosteres of para-disubstituted benzene because they impart valuable pharmacokinetic …

Abstract The 1, 2-arylheteroaryl ethane motif stands as a privileged scaffold with promising
implications in drug discovery. Conventional de novo syntheses of these molecules have …

Cyclopropanes bearing contiguous all-carbon quaternary centers continue to attract
attention due to their bioactivities. However, methods to obtain cyclopropanes with …

Radical remote 1, n-difunctionalization reactions (n> 2) of alkenes are powerful tools to
efficiently introduce functional groups with selected distances into target molecules. Among …

A practical electrochemical strategy for the direct synthesis of arenesulfonyl fluorides from
industrial feedstock nitroarenes is described. The key to success lies in using a cheap ionic …

Sulfonyl and sulfonimidoyl fluorides are versatile substrates in organic synthesis and
medicinal chemistry. However, they have been exclusively used as S (VI)+ electrophiles for …

An electroreductive strategy for radical hydroxyl fluorosulfonylation of alkenes with sulfuryl
chlorofluoride and molecular oxygen from air is described. This mild protocol displays …

Herein, we disclose a facile and versatile trifluoromethylimination of alkene with a rationally
designed N-(diphenylmethylene)-1, 1, 1-trifluoromethanesulfonamide as a bench-stable and …