Corneal stromal repair and regeneration

RR Mohan, D Kempuraj, S D'Souza, A Ghosh - Progress in retinal and eye …, 2022 - Elsevier
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

Mass spectrometry analysis of human tear fluid biomarkers specific for ocular and systemic diseases in the context of 3P medicine

X Zhan, J Li, Y Guo, O Golubnitschaja - EPMA Journal, 2021 - Springer
Over the last two decades, a large number of non-communicable/chronic disorders reached
an epidemic level on a global scale such as diabetes mellitus type 2, cardio-vascular …

Vitamin D and ocular diseases: a systematic review

HN Chan, XJ Zhang, XT Ling, CHT Bui… - International journal of …, 2022 - mdpi.com
The contributory roles of vitamin D in ocular and visual health have long been discussed,
with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper …

Tear biomarkers in dry eye disease: Progress in the last decade

NR Kumar, M Praveen, R Narasimhan… - Indian journal of …, 2023 - journals.lww.com
Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration

M Gijs, IHGB Ramakers, PJ Visser, FRJ Verhey… - Scientific reports, 2021 - nature.com
There has been increasing interest in finding non-invasive biomarkers for
neurodegenerative diseases such as Alzheimer's disease (AD). This observational study …

Hormones and dry eye disease

B Gorimanipalli, P Khamar, S Sethu… - Indian Journal of …, 2023 - journals.lww.com
The endocrine system influences all tissues and cells in the human body. The ocular surface
is constantly exposed to circulating hormones and expresses their specific receptors. Dry …

Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile

S D'Souza, AP Nair, GR Sahu, T Vaidya, R Shetty… - Scientific Reports, 2021 - nature.com
Inflammatory factors have been considered to contribute to keratoconus (KC) pathogenesis.
This study aims to determine the immune cells subsets and soluble inflammatory factor …

Dry eye disease: what is the role of vitamin D?

M Rolando, S Barabino - International Journal of Molecular Sciences, 2023 - mdpi.com
Dry eye disease (DED) is a multifactorial condition resulting from reduced tear secretion
from the lacrimal glands, increased tear water evaporation or the production of poor-quality …

Altered ocular surface immune cell profile in patients with dry eye disease

AP Nair, S D'Souza, R Shetty, P Ahuja, G Kundu… - The Ocular Surface, 2021 - Elsevier
Purpose Aberrant inflammation and immune dysregulation are known pathogenic
contributors in dry eye disease (DED). Aim of the study was to determine the proportions of …

A review of topical and systemic vitamin supplementation in ocular surface diseases

P Fogagnolo, S De Cilla', M Alkabes, P Sabella… - Nutrients, 2021 - mdpi.com
In the homeostasis of the ocular surface, vitamins play a critical role in regulating
inflammatory responses and promoting cell differentiation, development and correct …